Polisseur Biopak®
Ultrafiltre pour une eau exempte de pyrogènes, de nucléases et de bactéries au point de distribution
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Références bibliographiques
| Aperçu de la référence bibliographique | Nº PubMed |
|---|---|
| Polishing Up On Water Quality C. Devaux, C. Monferran, M. Tarun, E. Riche, D. Darbouret Laboratory Equipment – Chromatography Techniques (2010) Dec. 2009 Afficher le résumé Water plays a critical role in many analytical methods—particularly in the preparation of samples, standards, blanks, and eluents. It is crucial that water used for these applications does not introduce any impurities that could interfere with analytical results. As modern analytical instruments become capable of detecting ever increasingly low concentrations of analytes, ensuring the lowest level of background interference has become even more important—and more difficult. To meet this challenge, laboratory water purification systems have evolved accordingly. Current systems such as the Milli-Q Integral use a sophisticated combination of purification technologies to reduce ions, organics and other potentially background-causing contaminants to extremely low levels (i.e., 18.2 MΩ.cm resistivity and <5 µg/mL of TOC). Article en texte intégral | |
| Endotoxin-Free Water for Tissue Culture E. Riché, J. Bôle and S. Mabic Lab Manager Magazine (2010) May 2009 Afficher le résumé Water is a ubiquitous solvent used throughout cell isolation and culture. Therefore, water contamination may affect experimental outcomes. The use of ultrapure water is advisable for culturing of cells sensitive to environmental contaminants, such as endotoxins and bacteria. Cardiomycyte isolation experiments showed that using water contaminated with bacteria and endotoxins decreases cell viability, while using freshly produced ultrapure water dramatically increases it. Additionally, an ultrafiltration cartridge will efficiently remove large molecules that may be present in water. Article en texte intégral | |
| Water quality in patient testing J. Long and S. Mabic Clinical Lab Products (2007) April, 22-23 2007 Afficher le résumé Sophisticated diagnostic equipment is designed to improve quality, increase throughput, and manage continued labor shortages. All diagnostic manufacturers can provide the end user with software specifications that simplify automatic sampling and predilution; ensure workflow efficiency with high-speed throughput and performance; provide accuracy in testing with precision optical systems; deliver real-time access and alerts for patient and QC packages; and offer mechanical alerts to any possible instrumentation failures. Additionally, troubleshooting instrumentation, even with the above solution, creates unique challenges for medical technologists. Instrumentation can alert, flag, and warn that something is problematic, but it takes an experienced medical technologist to determine the root cause. One parameter, even though utilized by each end user on any kind of diagnostic instrument, has not been considered: water. Used in a variety of assays, water is a major reagent in clinical chemistry and immunoassay testing. Analytical factors linked to water quality need to be controlled and optimized to reduce the number of test failures. The water quality delivered to the analyzer is as important as any other reagent. Control of bacteria and its by-products with Elix technology and Biopak filters provides the highest quality water to be used in assays sensitive to these contaminants. Control of the water quality eliminates frequent decontamination. This optimizes analyzer performance and reduces downtime that can be costly to the customer and analyzer manufacturer. | Water quality in patient testing
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| Increased Flexibility in the Delivery of Ultrapure Water S. Mabic, D. Darbouret and J.F. Pilette Nature Methods (2006) 3 v-vi 2005 Afficher le résumé The Milli-Q Advantage system offers flexibility in the quality and delivery of various ultrapure water grades in laboratories. A single purification unit can be connected to up to three point-of-use dispensers, which can be equipped with different purifiers to provide the necessary water quality for various applications. The management of diverse and specific needs within the laboratory has been a driving force in developing this unique water purification system. This combination of technologies provides high-quality water with low TOC and high resistivity. Finally, this breadth of point-of-use purifiers addresses emerging needs as well as those for existing applications. Article en texte intégral | |
| Optimized POU device for the removal of RNases and endotoxins in high purity water Mabic, Stephane, Daniel Darbouret, and Ichiro Kano Ultrapure Water, March 2003: 53-59 2003 Afficher le résumé Performances of a disposable point-of-use (POU) UF device are described here, in terms of endotoxin and RNase removal. Following a brief description of technical features and data on extractables, the efficiency of the UF on endotoxin and RNase removal is illustrated with a number of typical experiments. |
Produits & Applications associés
Produits associés classés par : Application Facete
| Dialysis and Filtration |
Produits associés classés par : Brand Facete
| BioPak® |
Catégories
| Lab Water Purification > Lab Water Purification Consumables > Application-Paks |
Le polisseur Biopak® est conçu pour s'adapter sur la sortie des systèmes de purification d'eau, telle que les POD des systèmes Milli-Q®. Il est garanti pour une période d'utilisation allant jusqu'à trois mois. L'ultrafiltre est composé de fibres creuses en polysulfone dont la structure a été optimisée pour rejeter efficacement les contaminants ciblés, tout en maintenant un débit élevé et en minimisant la libération de matières ioniques et organiques.
Eau apyrogène et exempte de bactéries
Les pyrogènes sont connus pour affecter les cultures cellulaires et les expériences de biochimie de nombreuses manières. Les pyrogènes les plus courants provenant de bactéries sont les endotoxines (ou LPS pour lipopolysaccharides). Dans l'eau ultra pure, les LPS s'agrègent pour former des structures de poids moléculaire élevé qui peuvent être efficacement éliminées par des membranes d'ultrafiltration. Des expériences ont validé que le polisseur Biopak® pouvait être utilisé pendant au moins 90 jours* pour purifier l'eau ultra pure afin d'obtenir des niveaux de pyrogènes inférieurs à 0,001 EU/ml.
Eau dépourvue de nucléases
Les biologistes moléculaires ont systématiquement besoin de réactifs exempts de nucléases, car les molécules d'acides nucléiques sont au cœur de leurs recherches expérimentales. L'ultrafiltration Biopak® s'avère être une solution efficace et pratique pour ces scientifiques. D'autre part, l'ultrafiltration ne présente pas les inconvénients du DEPC (diéthylpyrocarbonate), à savoir la durée de traitement et la contamination de l'eau traitée par du CO2 et de l'éthanol. Des essais de challenge ont validé l'efficacité de Biopak® dans l'élimination des RNases (< 1 pg/ml) et des DNases (< 5 pg/ml). Chaque polisseur Biopak® est livré avec un certificat de qualité.
*Utilisation continue dans des conditions de test appropriées
Polisseur Biopak®
| Membrane | Membrane d'ultrafiltration à fibre creuse |
| Matériau du support | Acrylonitrile Butadiène Styrène (ABS) |
| Raccord d'entrée | ¼" Gaz (droit) |
| Raccord de sortie | Tuyau 8 mm (avec cloche protectrice) |