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07-441-AF488 Anti-dimethyl-Histone H3 (Lys9) Antibody, AlexaFluor® 488 Conjugate

Anti-dimethyl-Histone H3 (Lys9) Antibody, AlexaFluor® 488 Conjugate is an antibody against dimethyl-Histone H3 (Lys9) Antibody for use in Immunocytochemistry.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Nuclear Receptors Gene Symbol: HIST3H3, H3FT UniProt Number: Q16695
07-441-AF488
100 µL  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MICCRbAlexaFluor®488Polyclonal Antibody
Description
Catalogue Number07-441-AF488
DescriptionAnti-dimethyl-Histone H3 (Lys9) Antibody, AlexaFluor® 488 Conjugate
Alternate Names
  • Histone H3.1t
  • H3/t
  • H3t
  • H3/g
  • dimethyl-Histone H3 (Lys9), AlexaFluor® 488 Conjugate
Background InformationHistone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine and the phosphorylation of serine or threonine. Histone H3 variants (H3.1, H3.2 and H3.3) have been implicated in the epigenetic memory of cellular state. Genome-wide patterns of H3 are dependent on amino acid sequence and change with cellular differentiation at developmentally regulated loci.
References
Product Information
FormatAlexaFluor®488
PresentationPurified rabbit antibody conjugate in PBS with 15 mg/ml BSA and 0.1 % sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-dimethyl-Histone H3 (Lys9) Antibody, AlexaFluor® 488 Conjugate is an antibody against dimethyl-Histone H3 (Lys9) Antibody for use in Immunocytochemistry.
Key Applications
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: A 1:100 dilution from a representative lot detected dimethyl-Histone H3 (Lys9) in HepG2 cells.
The unconjugated antibody (Cat. No. 07-441) is shown to be suitable also for Western blotting, dot blot, immunocytochemistry, and peptide inhibition assay (peptide blocking) applications.
Biological Information
ImmunogenKLH-conjugated, 2X-branched synthetic peptide containing the sequence ..RKme2STG.., in which Kme2 corresponds to dimethyl-lysine at residue 9 of human Histone H3.
EpitopeH3K9me2
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityHistone H3 dimethylated on lysine 9.
Species Reactivity
  • Human
  • Mouse
Species Reactivity NoteHuman, Mouse. Predicted to react with Yeast, Rat, Chicken based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • HIST3H3
  • H3FT
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~17 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected dimethyl-Histone H3 (Lys9) in HeLa cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
07-441-AF488 04055977294798

Documentation

Anti-dimethyl-Histone H3 (Lys9) Antibody, AlexaFluor® 488 Conjugate FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Anti-dimethyl-Histone H3 (Lys9) Antibody, AlexaFluor® 488 Conjugate Certificats d'analyse

TitreNuméro de lot
Anti-dimethyl-Histone H3 (Lys9), AlexaFluor® 488 Conjugate 2868340
Anti-dimethyl-Histone H3 (Lys9), AlexaFluor® 488 Conjugate - 3198393 3198393
Anti-dimethyl-Histone H3 (Lys9), AlexaFluor® 488 Conjugate - 4133766 4133766
Anti-dimethyl-Histone H3 (Lys9), AlexaFluor® 488 Conjugate -Q2611355 Q2611355

Brochure

Titre
New Products Flyer- Vol 4 Signaling Feature- NEW! Phosphohistidine Antibody

Posters

Titre
Post-Translational Modifications