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MAB930-I Anti-Staphylococcus aureus Antibody, clone STAPH 11-248.2

MAB930-I
100 μg  
Purchase on Sigma-Aldrich

Aperçu

Replacement Information
Description
Catalogue NumberMAB930-I
DescriptionAnti-Staphylococcus aureus Antibody, clone STAPH 11-248.2
Alternate Names
  • S.Sureus
Background InformationStaphylococcus aureus is cocci-shaped Gram-positive bacteria that is the causative agent of multiple human infections, including bacteremia, infective endocarditis, skin and soft tissue infections.

Although S. aureus is not always pathogenic but is a common cause of skin infections such as abscesses, respiratory infections, and food poisoning. Pathogenic strains often promote infections by producing potent protein toxins and expressing cell-surface proteins that bind and inactivate antibodies. Its mechanisms for evasion of the host immune response include the production of an antiphagocytic capsule, sequestering of host antibodies or antigen masking by Protein A, biofilm formation, intracellular survival, and blocking chemotaxis of leukocytes. Infection by S.aureus involves colonization, local infection, systemic dissemination and/or sepsis, metastatic infection, and toxinosis.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal in buffer containing PBS, pH 7.4, containing no preservatives.
Quality LevelMQ100
Applications
ApplicationAnti-Staphylococcus aureus, clone STAPH 11-248.2, Cat. No. MAB930-I, is a mouse monoclonal antibody that detects Staphylococcus aureus and is tested for use in ELISA.
Key Applications
  • ELISA
Application NotesELISA: (Dilution is assay based)

Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user
Biological Information
ImmunogenUV-inactivated Staphylococcus aureas cells (ATCC# 29740).
EpitopeUnknown
CloneSTAPH 11-248.2
ConcentrationPlease refer to guidance on suggested starting dilutions and/or titers per application and sample type.
HostMouse
SpecificityClone STAPH 11-248.2 is a mouse monoclonal antibody that specifically detects Staphylococcus aureus. It does not display any cross-reactivity with Streptococcus sp., Mycoplasma sp., or Corynebacteria sp.
IsotypeIgM
Species Reactivity
  • Bacteria
Species Reactivity NoteStaphylococcus aureus.
Antibody TypeMonoclonal Antibody
Gene Symbol
  • N/A
Purification MethodPEG-purified.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at +2°C to +8°C from date of receipt.


Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
MAB930-I 04065265651530