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AB5603-AF647 Anti-Sox2 Antibody, Alexa Fluor® 647 Conjugate

This Anti-Sox2 Antibody, Alexa Fluor® 647 Conjugate is validated for use in Immunocytochemistry for the detection of Sox2.

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Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: SOX2, ANOP3, MCOPS3 UniProt Number: P48431
AB5603-AF647
100 µL  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MICCRbAlexaFluor®555Polyclonal Antibody
Description
Catalogue NumberAB5603-AF647
DescriptionAnti-Sox2 Antibody, Alexa Fluor® 647 Conjugate
Alternate Names
  • Transcription factor SOX-2
  • Sex determining region Y-box 2
  • SRY-related HMG-box gene 2
  • Transcription factor SOX2
Background InformationTranscription factor SOX-2 (UniProt P48431; also known as Sex determining region Y-box 2, SRY-related HMG-box gene 2, Transcription factor SOX2) is encoded by the SOX2 (also known as ANOP3, MCOPS3) gene (Gene ID 6657) in human. Sox family of genes are related to the mammalian sex determining gene SRY. These genes contain sequences that encode for the HMG-box domains that mediate sequence-specific DNA binding. Sox genes encode transcriptional regulators involved in cell fate decision during development and the control of diverse developmental processes. At least 30 Sox genes have been identified. Sox2 plays an essential role in maintaining the pluripotency and self-renewal of undifferentiated embryonic stem cells.
References
Product Information
FormatAlexaFluor®555
PresentationPurified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Sox2 Antibody, Alexa Fluor® 647 Conjugate is validated for use in Immunocytochemistry for the detection of Sox2.
Key Applications
  • Immunocytochemistry
Application NotesThe unconjugated antibody (Cat. No. AB5603) is shown to be suitable also for Western blotting and immunocytochemistry applications.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to a C-terminal region sequence of human Sox2.
EpitopeC-terminal region.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • SOX2
  • ANOP3
  • MCOPS3
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~39 kDa observed.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in mouse ESCs.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Sox2 in mouse ESCs.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
AB5603-AF647 04055977314748