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MABC189 Anti-PIDD Antibody, clone 1511.1

Anti-PIDD Antibody, clone 1511.1 is a highly specific mouse monoclonal antibody, that targets p53-induced protein with a death domain & has been tested in western blotting & ICC.

Anti-PIDD Antibody, clone 1511.1 : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: PIDD, LRDD UniProt Number: Q9HB75
MABC189
100 µg  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, ICCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC189
DescriptionAnti-PIDD Antibody, clone 1511.1
Alternate Names
  • p53-induced protein with a death domain
  • Leucine-rich repeat and death domain-containing protein
  • PIDD
Background Informationp53-induced protein with a death domain (PIDD) is also called Leucine-rich repeat and death domain-containing protein (LRDD). PIDD is involved in apoptosis downstream of the tumor suppressor. PIDD is a component of the DNA damage/stress response pathway in which p53/TP53 is associated with apoptosis. PIDD also aids in the activation of the transcription factor NF-kappa-B, and CASP2 which regulates apoptotic pathways.
References
Product Information
FormatPurified
Control
  • HeLa cell lysate
PresentationPurified mouse IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-PIDD Antibody, clone 1511.1 is a highly specific mouse monoclonal antibody, that targets p53-induced protein with a death domain & has been tested in western blotting & ICC.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesWestern Blotting Analysis: 1 µg/mL from a representative lot detected PIDD in 10 µg of NIH/3T3 and PC-12 cell lysate.

Immunohistochemistry Analysis: A 1:100 dilution, a 1:500 dilution, and a 1:1,000 dilution detected PIDD in HeLa, A431, and NIH/3T3 cells.
Biological Information
ImmunogenRecombinant protein corresponding to human PIDD.
Clone15F11.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody demonstrates specificity for isoform 4, but may detect isoform 1, 2 and 3. It will not detect isoforms 5, 6, and 7 based upon immunogen design.
IsotypeIgG1κ
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PIDD
  • LRDD
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~66 kDa observed. Uniprot describes 7 different isoforms.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected PIDD in 10 µg of HeLa cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
MABC189 04053252916953