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MABS1966-25UG Anti-PEG Antibody, clone 6.3

MABS1966-25UG
25 μg  
Purchase on Sigma-Aldrich

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Replacement Information
Description
Catalogue NumberMABS1966-25UG
DescriptionAnti-PEG Antibody, clone 6.3
Alternate Names
  • Polyethylene Glycol
Background InformationPolyethylene glycols (PEG) are non-toxic, uncharged, hydrophilic long chain polymers with a big exclusion volume in aqueous solution. The covalent attachment of PEG is commonly employed to modify proteins and drugs that can increase their bioavailability and reduce immunogenicity and proteolytic degradation. Clone 6.3 displays high affinity and binds the PEG backbone and can be employed as a detection antibody for the quantification of PEG. It binds to a smaller epitope of the PEG backbone when compared to other antibodies. Since it binds to a smaller PEG epitope (~750 Da), it is not compatible with detergents that contain an ethylene oxide backbone, such as Tween 20. Instead 0.05% CHAPS is a more suitable detergent when using this antibody.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal antibody IgG1 in PBS with 0.04% sodium azide.
Applications
ApplicationAnti-PEG, clone 6.3, Cat. No. MABS1966, is a mouse monoclonal antibody that detects PEG-conjugated proteins and it hs been tested for use in ELISA.
Key Applications
  • ELISA
Application NotesELISA Analysis: A representative lot detected PEG in ELISA applications (Tung, H.Y., et. al. (2015). Mol Cancer Ther. 14(6):1317-26).
Biological Information
ImmunogenPEG-conjugated to E.coli beta-glucuronidase.
Clone6.3
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityClone 6.3 specifically detects proteins conjugated with polyethylene glycol (PEG).
IsotypeIgG1κ
Species Reactivity
  • All
Species Reactivity NoteAll.
Antibody TypeMonoclonal Antibody
Purification MethodProtein A purified
Molecular WeightN/A
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by ELISA in Immobilized PEG (10K-PEG, 3K-PEG, and 2K-mPEG).

ELISA Analysis: 5 µg/mL of Immobilized PEG (10K-PEG, 3K-PEG, and 2K-mPEG) were detected with this antibody.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size25 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
MABS1966-25UG 04054839607691

Documentation

Anti-PEG Antibody, clone 6.3 FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Anti-PEG Antibody, clone 6.3 Certificats d'analyse

TitreNuméro de lot
Anti-PEG, clone 6.3 - 3502134 3502134
Anti-PEG, clone 6.3 - 3714319 3714319
Anti-PEG, clone 6.3 - 3821572 3821572
Anti-PEG, clone 6.3 - 3888853 3888853
Anti-PEG, clone 6.3 - 3943931 3943931
Anti-PEG, clone 6.3 - 3977224 3977224
Anti-PEG, clone 6.3 - 3999960 3999960
Anti-PEG, clone 6.3 - 4020048 4020048
Anti-PEG, clone 6.3 - 4042199 4042199
Anti-PEG, clone 6.3 - 4107794 4107794