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ABT317 Anti-Matriptase-2/TMPRSS6 Antibody

Anti-Matriptase-2/TMPRSS6 Antibody is an antibody against Matriptase-2/TMPRSS6 for use in western blotting & IHC.

Anti-Matriptase-2/TMPRSS6 Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: TMPRSS6 UniProt Number: Q8IU80
ABT317
100 µL  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT317
DescriptionAnti-Matriptase-2/TMPRSS6 Antibody
Alternate Names
  • Transmembrane protease serine 6
  • Matriptase-2
Background InformationMatriptase-2/TMPRSS6, also known as Transmembrane protease serine 6, and encoded by the gene TMPRSS6, is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen and appears to play an important role in matrix remodeling in the liver. Matriptase-2/TMPRSS6 also plays an important role in iron homeostasis and interacts with the iron homeostasis protein Hepcidin. Maintaining the body’s levels of iron within precise boundaries is essential for normal physiological function. Alterations of these levels below or above the healthy limit lead to a systemic deficiency or overload in iron. Matriptase-2/TMPRSS6 is a proteolytic regulator of iron homeostasis. Matriptase-2/TMPRSS6 is expressed only in the liver in normal tissues and undergoes proteolytic processing to yield two activated chains that are shed one intracellularly and one extracellularly. Mutations in Matriptase-2/TMPRSS6 gene give rise to iron deficiency anemia.
References
Product Information
FormatAffinity Purified
HS Code3002 15 90
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Matriptase-2/TMPRSS6 Antibody is an antibody against Matriptase-2/TMPRSS6 for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Matriptase-2/TMPRSS6 in human liver and mouse liver tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Matriptase-2/TMPRSS6 near the C-terminal.
EpitopeNear C-terminal
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • TMPRSS6
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~52 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in MCF-7 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Matriptase-2/TMPRSS6 in 10 µg of MCF-7 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
ABT317 04053252958212

Documentation

Anti-Matriptase-2/TMPRSS6 Antibody FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Anti-Matriptase-2/TMPRSS6 Antibody Certificats d'analyse

TitreNuméro de lot
Anti-Matriptase-2/TMPRSS6 - Q2388152 Q2388152
Anti-Matriptase-2/TMPRSS6 - 3267943 3267943
Anti-Matriptase-2/TMPRSS6 - 3385860 3385860
Anti-Matriptase-2/TMPRSS6 - 3750159 3750159
Anti-Matriptase-2/TMPRSS6 - 3862695 3862695
Anti-Matriptase-2/TMPRSS6 -2747993 2747993
Anti-Matriptase-2/TMPRSS6 -2851769 2851769
Anti-Matriptase-2/TMPRSS6 -2854630 2854630
Anti-Matriptase-2/TMPRSS6 -2891890 2891890
Anti-Matriptase-2/TMPRSS6 Polyclonal Antibody 2983254
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