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ABN213 Anti-IL-12 alpha Antibody

ABN213
100 µg  
Purchase on Sigma-Aldrich

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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN213
ReplacesMABN1084
DescriptionAnti-IL-12 alpha Antibody
Alternate Names
  • Interleukin-12 subunit alpha
  • IL-12A
  • Cytotoxic lymphocyte maturation factor 35 kDa subunit
  • CLMF p35
  • IL-12 subunit p35
  • NK cell stimulatory factor chain 1
  • NKSF1
Background InformationInterleukin-12 alpha (IL-12A) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35), IL-12 subunit p35, or NK cell stimulatory factor chain 1 (NKSF-1). IL-12A is a cytokine that, along with IL12B, forms a disulfide-linked heterodimer interleukin IL-12. IL-12 alpha functions as a regulator of T cell mediated cytotoxicity, interferon-gamma production, lymphocyte proliferation and activation of natural killer cells.
References
Product Information
FormatAffinity Purified
Control
  • Human lymph node tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis IL-12 alpha antibody is validated for use in WB & IHC for the detection of the IL-12 alpha protein.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:16,000-32,000 dilution from a representative lot detected IL-12 alpha in human tonsil and human brain tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the near C-terminus of human IL-12 alpha.
EpitopeNear C-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the near C-terminus of IL-12 alpha
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • IL12A
  • NKSF1
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~25 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human lymph node tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected IL-12 alpha in 10 µg of human lymph node tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
ABN213 04053252859311