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AB9858 Anti-GPCR G2A Antibody

Detect GPCR G2A using this Anti-GPCR G2A Antibody validated for use in IH(P).

Anti-GPCR G2A Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Neuroscience Research Sub-Category: Growth Cones & Axon Guidance Gene Symbol: GPR132, G2A, MGC99642 UniProt Number: Q9UNW8
AB9858
25 µg  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
RIH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9858
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-GPCR G2A Antibody
Alternate Names
  • G protein-coupled receptor G2A
References
Product Information
FormatAffinity Purified
PresentationAffinity purified immunoglobulin. Liquid in 0.1M Glycine / 0.2M Tris buffer solution pH7.8 containing 0.02% sodium azide.
Quality LevelMQ300
Applications
ApplicationDetect GPCR G2A using this Anti-GPCR G2A Antibody validated for use in IH(P).
Key Applications
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry on formalin fixed, paraffin embedded rat cerebellum.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenHighly purified peptide from C-terminus of rat G2A.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes rat GPCR G2A (G protein-coupled receptor G2A
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression.
Gene Symbol
  • GPR132
  • G2A
  • MGC99642
Purification MethodImmunoAffinity Purified
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q9UNW8 # Receptor for an unknown ligand. Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication.
SIZE: 380 amino acids; 42499 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (Probable). Note=Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface (By similarity).
TISSUE SPECIFICITY: Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region.
SIMILARITY: SwissProt: Q9UNW8 ## Belongs to the G-protein coupled receptor 1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Packaging Information
Material Size25 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
AB9858 04053252372698