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MAB1217-I Anti-Fmc-7 (B-Cell Lymphocyte Marker), clone Fmc-7 Antibody

This Anti-Fmc-7 (B-Cell Lymphocyte Marker) antibody is validated for use in WB, FC for the detection of Fmc-7 (B-Cell Lymphocyte Marker).

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Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology
MAB1217-I
100 tests  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, FCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB1217-I
DescriptionAnti-Fmc-7 (B-Cell Lymphocyte Marker), clone Fmc-7 Antibody
Background InformationB cells are lymphocytes that play a large role in the humoral immune response as opposed to the cell-mediated immune response that is governed by T cells. The principal function of B cells is to make antibodies against soluble antigens. B cells are an essential component of the adaptive immune system. FMC-7 B-Cell Lymphocyte Marker is a 105 kDa B cell restricted antigen which is expressed on about 50% of adult human peripheral blood B cells. Upon in vivo B cell activation FMC7 expression initially increases. B cells involved in antibody secretion have lost the FMC7 determinant. The monoclonal antibody FMC7 delineates a subpopulation of B lymphocytes in normal blood. Expression of the antigen recognized by FMC7 appears to be maturation-linked, and it serves to distinguish different types of B cell leukemia.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgMκ in buffer containing 0.1M Tris, 10mM Glycine, 0.5M NaCl, and 0.1% Sodium Azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Fmc-7 (B-Cell Lymphocyte Marker) antibody is validated for use in WB, FC for the detection of Fmc-7 (B-Cell Lymphocyte Marker).
Key Applications
  • Western Blotting
  • Flow Cytometry
Application NotesFlow Cytometry Analysis: 4.0 µg of this antibody detected Fmc-7 (B-Cell Lymphocyte Marker) in peripheral blood mononuclear cells.
Biological Information
ImmunogenHRIK [human B-lymphoblastoid cell] corresponding to human Fmc-7 (B-Cell Lymphocyte Marker).
CloneFmc-7
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgMκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Purification MethodAmmonium Sulfate
Molecular Weight~105 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in THP-1 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Fmc-7 (B-Cell Lymphocyte Marker) in 10 µg of THP-1 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
MAB1217-I 04055977109276