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ABS811 Anti-FABP7 Antibody

ABS811
100 μg  
Purchase on Sigma-Aldrich

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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS811
ReplacesMABS184
DescriptionAnti-FABP7 Antibody
Alternate Names
  • Fatty acid-binding protein
  • brain
  • Brain lipid-binding protein
  • BLBP
  • Brain-type fatty acid-binding protein
  • B-FABP
  • Fatty acid-binding protein 7
  • Mammary-derived growth inhibitor related
  • FABP7
Background InformationFABP7 is a member of the large family of hydrophobic ligand-binding proteins (FABPs). FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids. In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation. Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy. Nine FABPs (FABP1-FABP9) have been identified. FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. It is expressed at high levels in the developing central nervous system. FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-FABP7 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of FABP7.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis (IHC): 5 μg/mL from a representative lot detected FABP7 in human breast tissue.

Biological Information
ImmunogenFABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7.
EpitopeNear Center
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • FABP7
  • BLBP
  • FABPB
  • MRG
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~24 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human breast tissue lysate.

Western Blotting Analysis (WB): 1 μg/mL of this antibody detected FABP7 in human breast tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
ABS811 04055977174694

Documentation

Anti-FABP7 Antibody FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Anti-FABP7 Antibody Certificats d'analyse

TitreNuméro de lot
Anti-FABP7 - VP1904036 VP1904036
Anti-FABP7 -QVP1503132 QVP1503132
Anti-FABP7 -VP1606162 VP1606162
Anti-FABP7 -VP1609039 VP1609039
Anti-FABP7 Polyclonal Antibody VP1808024

Informations techniques

Titre
Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
White Paper: Further considerations of antibody validation and usage.