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MABS1694 Anti-FABP2 Antibody, clone 4F6.1

Detect FABP2 using this mouse monoclonal Anti-FABP2 Antibody, clone 4F6.1, Cat. No. MABS1694, validated for use in Immunohistochemistry (Paraffin) and Western Blotting.

Anti-FABP2 Antibody, clone 4F6.1 : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Signaling Gene Symbol: FABP2, FABPI UniProt Number: P12104
MABS1694
100 µL  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, M, HIH(P), WBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABS1694
DescriptionAnti-FABP2 Antibody, clone 4F6.1
Alternate Names
  • Fatty acid-binding protein
  • intestinal
  • Fatty acid-binding protein 2
  • I-FABP
  • Intestinal-type fatty acid-binding protein
Background InformationFatty acid-binding protein, intestinal (UniProt P12104; also known as Fatty acid-binding protein 2, I-FABP, Intestinal-type fatty acid-binding protein) is encoded by the FABP2 (also known as FABPI) gene (Gene ID 2169) in human. The intracellular lipid-binding protein (iLBP) multigene family includes 12 fatty acid-binding protein (FABPs), 4 retinol-binding proteins (RBPs) and 2 cellular retinoic acid-binding proteins (CRABPs). FABPs are 14-16 kDa cytosolic proteins that bind fatty acids (FAs) and other hydrophobic ligands, such as eicosanoids and retinoids. FABPs are either numbered by the Hertzel and Bernlohr nomenclature to indicate their chronological order of discovery or named according to the tissue where each FABP was first isolated. In addition to transporting and sequestering long-chain FAs, eicosanoids, bile salts, and other hydrophobic ligands for storage and metabolism, FABPs are long recognized for their role in gene transcription regulation via lipid-mediated activation of nuclear hormone receptors (NHRs). FABP1 and FABP2, for example, are shown to bind a range of PPAR agonists, including long chain fatty acids (LCFA) and drugs. FABPs play differential and ligand-specific roles in NHR activation, and the patterns of drug interaction with intracellular binding proteins such as FABPs may govern tissue-specific actions of drugs that target NHRs.
References
Product Information
FormatPurified
PresentationPurified mouse IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect FABP2 using this mouse monoclonal Anti-FABP2 Antibody, clone 4F6.1, Cat. No. MABS1694, validated for use in Immunohistochemistry (Paraffin) and Western Blotting.
Key Applications
  • Immunohistochemistry (Paraffin)
  • Western Blotting
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative detected FABP2 in human small intestine and rat colon tissue sections.

Western Blotting Analysis: A 1:1,000 dilution from a representative detected FABP2 in 10 µg of human small intestine tissue lysate.
Biological Information
ImmunogenGST-tagged recombinant human FABP2.
Clone4F6.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityClone 4F6.1 targets an epitope conserved among human, mouse, and rat species.
IsotypeIgG1κ
Species Reactivity
  • Rat
  • Mouse
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • FABP2
  • FABPI
Purification MethodProtein G purified.
UniProt Number
Molecular Weight~15 kDa observed. 15.11 kDa (human), 14.99 kDa (mouse & rat) calculated (Met1 removed). Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse small intestine tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FABP2 in 10 µg of mouse small intestine tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
MABS1694 04054839056260