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MABC1036 Anti-EphA7 Antibody, clone 2F3.1

Anti-EphA7 Antibody, clone 2F3.1 is an antibody against EphA7 for use in Western Blotting.

Anti-EphA7 Antibody, clone 2F3.1 : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Cytokines & Cytokine Receptors Gene Symbol: EPHA7, EHK3, HEK11 UniProt Number: Q15375
MABC1036
100 μg  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC1036
DescriptionAnti-EphA7 Antibody, clone 2F3.1
Alternate Names
  • Ephrin type-A receptor 7
  • EHK-3
  • EK11
  • EPH homology kinase 3
  • EPH-like kinase 11
  • hEK11
  • Receptor protein-tyrosine kinase HEK11
  • Tyrosine-protein kinase receptor EHK-3
Background InformationEphrin type-A receptor 7 (EC 2.7.10.1; UniProt Q15375; also known as EHK-3, EK11, EPH homology kinase 3, EPH-like kinase 11, hEK11, Receptor protein-tyrosine kinase HEK11, Tyrosine-protein kinase receptor EHK-3) is encoded by the EPHA7 (also known as EHK3, HEK11) gene (Gene ID 2045) in human. EphA7 belongs to the ephrin receptor family of receptor tyrosine kinases that are activated upon ephrin binding. Ephrin receptor signaling plays important roles in embryonic development, tissue boundaries formation, angiogenesis, stem cell differentiation, and cancer. There exist nine type-A (EphA1-8 and EphA10) and five type-B (EphB1-4 and EphB6) ephrin receptors in human. EphA7 is initially produced with a signal peptide (a.a. 1-27) sequence, the removal of which yields the mature protein with a large extracellular (a.a. 28-555) region, followed by a transmembrane segment (a.a. 556-576) and a cytoplasmic region (a.a. 577-998) that contains the kinase domain (a.a. 633-894).
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-EphA7 Antibody, clone 2F3.1 is an antibody against EphA7 for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenGST-tagged recombinant extracellular N-terminal fragment of human EphA7.
EpitopeExtracellular domain.
Clone2F3.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityExpected to react with all five spliced isoforms of human EphA7 reported by UniProt (Q15375).
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • EPHA7
  • EHK3
  • HEK11
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~120 kDa observed. 112.1 kDa (isoform 1; EPHA7-FL), 111.5 kDa (isoform 2), 31.83 kDa (isoform 3), 111.6 kDa (isoform 4), and 50.52 kDa (isoform 5; EPHA7-S) calculated.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in MCF-7 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected EphA7 in 10 µg of MCF-7 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
MABC1036 04055977330359