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ABS448 Anti-CSN8 Antibody

ABS448
100 µg  
Purchase on Sigma-Aldrich

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Replacement Information

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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS448
ReplacesMABN1028
DescriptionAnti-CSN8 Antibody
Alternate Names
  • CSN8 Antibody
  • COP9 signalosome complex subunit 8
  • SGN8
  • JAB1-containing signalosome subunit 8
  • CSN8
Background InformationCOP9 signalosome complex subunit 8 (CSN8, COPS8), also known as Signalosome subunit 8 (SGN8), is a nuclear-enriched protein complex belonging to the CSN8 family. It is comprised of eight subunits that interact with deubiquitinating enzymes and protein kinases. The CSN complex is involved in the regulation of various signaling and developmental processes, including DNA repair, cell cycle regulation, embryogenesis, axonal guidance, MAPK cascade, immune response, and hormonal signaling.
References
Product Information
FormatAffinity Purified
Control
  • Human liver tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-CSN8 Antibody is a highly specific rabbit polyclonal antibody, that targets COP9 signalosome complex subunit 8 & has been tested in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human CSN8.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of CSN8.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • COPS8
  • CSN8
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~27 and ~30 kDa observed. Uniprot describes 2 isoforms at ~18 kDa and ~23 kDa. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected CSN8 in 15 µg of human liver tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
ABS448 04053252901256