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07-262 Anti-Arg Antibody, SH3/SH2

Anti-Arg Antibody, SH3/SH2 is an antibody against Arg for use in IH, IP & WB.

Anti-Arg Antibody, SH3/SH2 : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Signaling Research Sub-Category: Insulin/Energy Signaling Gene Symbol: ABL2, Abelson-related, ABLL, ARG UniProt Number: P42684
07-262
200 µL  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
MIHC, IP, WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue Number07-262
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAnti-Arg Antibody, SH3/SH2
References
Product Information
FormatAffinity Purified
Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Applications
ApplicationAnti-Arg Antibody, SH3/SH2 is an antibody against Arg for use in IH, IP & WB.
Key Applications
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blotting
Biological Information
ImmunogenGST fusion protein corresponding to the SH2 and SH3 domains of murine Arg (Abl-related gene), residues 112-259
HostRabbit
SpecificityArg
IsotypeIgG
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe gene product is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. This gene is expressed in both normal and tumor cells. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Gene Symbol
  • ABL2
  • Abelson-related
  • ABLL
  • ARG
Purification MethodImmunoaffinity Chromatography
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P42684 # Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.
COFACTOR: Magnesium or manganese.
SIZE: 1182 amino acids; 128343 Da
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Widely expressed.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: P42684 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Molecular Weight135 & 140kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by immunoblot on RIPA lysates from Mouse Brain Cytosol
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions1 year at -20°C
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
07-262 04053252625114