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MABC680 Anti-AXL, clone 7E10 Antibody

Anti-AXL, clone 7E10 is an antibody against AXL for use in Western Blotting and Immunocytochemistry.

Anti-AXL, clone 7E10 Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: AXL, UFO UniProt Number: P30530
MABC680
100 µL  
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Tableau de caractéristiques principal

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ICCMAscitesMonoclonal Antibody
Description
Catalogue NumberMABC680
DescriptionAnti-AXL, clone 7E10 Antibody
Alternate Names
  • Tyrosine-protein kinase receptor UFO
  • AXL
Background InformationAXL receptor tyrosine kinase, also known as UFO, JTK11. AXL is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. AXL transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. AXL is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-AXL, clone 7E10 is an antibody against AXL for use in Western Blotting and Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis (ICC): A 1:200-1,000 dilution from a representative lot detected AXL in methanol-fixed HEK293 cells transfected with AXL-hIgGFc.
Biological Information
ImmunogenPurified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
Clone7E10
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • AXL
  • UFO
Purification MethodUnpurified
UniProt Number
Molecular Weight~67 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in extracellular domain of human AXL.

Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected AXL in the extracellular domain.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
MABC680 04055977172249