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171601 Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem

The Amyloid Precursor Protein β-Secretase Inhibitor controls the biological activity of Amyloid Precursor Protein β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: KTEETSEVN(stat)VAEF

Primary Target: APP
171601
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Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₇₃H₁₁₈N₁₆O₂₇

Products

RéférenceConditionnement Qté
171601-500UG Ampoule plast. 500 μg
Description
OverviewA potent inhibitor of the amyloid precursor protein (APP) β-secretase (IC50 = 30 nM).
Catalogue Number171601
Brand Family Calbiochem®
SynonymsKTEETSEVN(stat)VAEF
References
ReferencesSinha, S., et al. 1999. Nature 402, 537.
Product Information
ATP CompetitiveN
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₇₃H₁₁₈N₁₆O₂₇
Chemical formulaC₇₃H₁₁₈N₁₆O₂₇
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetAPP
Primary Target IC<sub>50</sub>30 nM against amyloid precursor protein (APP) β-secretase
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceH-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe-OH [Stat = (3S,4S)-Statine]
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
171601-500UG 04055977207293

Documentation

Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem Certificats d'analyse

TitreNuméro de lot
171601

Références bibliographiques

Aperçu de la référence bibliographique
Sinha, S., et al. 1999. Nature 402, 537.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-April-2008 RFH
SynonymsKTEETSEVN(stat)VAEF
DescriptionA potent inhibitor of the amyloid precursor protein (APP) β-secretase (IC50 = 30 nM).
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₇₃H₁₁₈N₁₆O₂₇
Peptide SequenceH-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe-OH [Stat = (3S,4S)-Statine]
Purity≥98% by HPLC
SolubilityAqueous Buffers (pH 7.5) (1 mg/ml).
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSinha, S., et al. 1999. Nature 402, 537.