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14-661 ARK5 Protein, active, 10 µg

14-661
10 µg  
Purchase on Sigma-Aldrich

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Replacement Information
Description
Catalogue Number14-661
Brand Family Upstate
Trade Name
  • Upstate
DescriptionARK5 Protein, active, 10 µg
OverviewN-terminal 6His-tagged, recombinant, human ARK5, amino acids 2-end
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, human ARK5, amino acids 2-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceExpressed by baculovirus in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • NUAK1
  • KIAA0537
  • ARK5
  • NuaK1
Protein TargetNuaK1 (ARK5)
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyCAMK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: O60285 # Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
COFACTOR: Magnesium.
SIZE: 661 amino acids; 74305 Da
TISSUE SPECIFICITY: Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.
SIMILARITY: SwissProt: O60285 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. & Contains 1 protein kinase domain.
Molecular Weight78kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of CHKtide
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 6 months at -70°C from date of shipment
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
14-661 04053252678288