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454202 8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem

A cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC₅₀ = 4 µM).

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 8-Methoxymethyl-IBMX

Primary Target: PDE 1
454202
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
78033-08-6C₁₂H₁₈N₄O₃

Products

RéférenceConditionnement Qté
454202-10MG Ampoule plast. 10 mg
Description
OverviewA cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC50 = 4 µM).
Catalogue Number454202
Brand Family Calbiochem®
Synonyms8-Methoxymethyl-IBMX
References
ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
Product Information
CAS number78033-08-6
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₂H₁₈N₄O₃
Chemical formulaC₁₂H₁₈N₄O₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPDE 1
Primary Target IC<sub>50</sub>4 µM against Ca2+-calmodulin-dependent phosphodiesterase (PDE I)
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
454202-10MG 04055977204742

Documentation

8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem Certificats d'analyse

TitreNuméro de lot
454202

Références bibliographiques

Aperçu de la référence bibliographique
Jackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-August-2008 RFH
Synonyms8-Methoxymethyl-IBMX
DescriptionA cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I, IC50 = 4 µM).
FormWhite solid
CAS number78033-08-6
Chemical formulaC₁₂H₁₈N₄O₃
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityDMSO (5 mg/ml) or Ethanol (2 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
Han, P., et al. 1989. J. Biol. Chem. 274, 22337.