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487910 (±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem

487910
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Aperçu

Tableau de caractéristiques principal

CAS #Empirical Formula
79032-48-7C₇H₁₂N₂O₄S

Products

RéférenceConditionnement Qté
487910-1SET Flacon en verre 1 set
487910-20MG Ampoule plast. 20 mg
Description
OverviewNitric oxide donor that mimics the actions of nitric oxide, including relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.
Catalogue Number487910
Brand Family Calbiochem®
SynonymsSNAP
References
ReferencesNishio, E., et al. 1996. Biochem. Biophys. Res. Commun. 221, 163.
Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
Fehsel, K., et al. 1995. J. Immunol. 155, 2858.
Gopalkrishna, R., et al. 1993. J. Biol. Chem. 268, 27180.
Southan, E., and Garthwaite, J. 1991. Neurosci. Lett. 130, 107.
Henry, P.J., et al. 1989. J. Pharmacol. Exp. Ther. 248, 762.
Product Information
CAS number79032-48-7
ATP CompetitiveN
FormPale green solid
Hill FormulaC₇H₁₂N₂O₄S
Chemical formulaC₇H₁₂N₂O₄S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetNitric oxide donor
Primary Target IC<sub>50</sub>EC50 = 130 nM in relaxation of isolated bovine coronary artery rings
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsSNAP evolves NO immediately upon solubilization; reconstitute just prior to use.
Global Trade Item Number
Référence GTIN
487910-1SET 04055977200324
487910-20MG 04055977200331