324880 Sigma-Aldrich(–)-Epigallocatechin Gallate - CAS 989-51-5 - Calbiochem
One of the main polyphenolic constituents of green tea that exhibits potent antitumor, anti-inflammatory, and antioxidant properties.
More>> One of the main polyphenolic constituents of green tea that exhibits potent antitumor, anti-inflammatory, and antioxidant properties. Less<<Synonymes: EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol-3-(3,4,5-trihydroxybenzoate), DNA Methyltransferase Inhibitor IV, HAT Inhibitor X, Histone Acetyltransferase Inhibitor X, p300/CBP Inhibitor VIII, PCAF Inhibitor V, DNA MTase Inhibitor IV
Produits recommandés
Aperçu
Replacement Information |
---|
Tableau de caractéristiques principal
CAS # | Empirical Formula |
---|---|
989-51-5 | C₂₂H₁₈O₁₁ |
Products
Référence | Conditionnement | Qté | |
---|---|---|---|
324880-10MG | Ampoule plast. | 10 mg |
Product Information | |
---|---|
CAS number | 989-51-5 |
ATP Competitive | N |
Form | Faint pink solid |
Hill Formula | C₂₂H₁₈O₁₁ |
Chemical formula | C₂₂H₁₈O₁₁ |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
---|
Biological Information | |
---|---|
Primary Target | PMA-induced skin thickening |
Primary Target IC<sub>50</sub> | 210-470 nM against Dnmt1; 30, 50, 60 and 70 µM for p300, CBP, PCAF and TIP60 |
Purity | ≥95% by HPLC |
Physicochemical Information | |
---|---|
Cell permeable | N |
Dimensions |
---|
Materials Information |
---|
Toxicological Information |
---|
Safety Information according to GHS | |
---|---|
RTECS | KB5200000 |
Product Usage Statements |
---|
Packaging Information | |
---|---|
Packaged under inert gas | Packaged under inert gas |
Transport Information |
---|
Supplemental Information |
---|
Specifications |
---|
Global Trade Item Number | |
---|---|
Référence | GTIN |
324880-10MG | 04055977196092 |
Documentation
(–)-Epigallocatechin Gallate - CAS 989-51-5 - Calbiochem FDS
Titre |
---|
(–)-Epigallocatechin Gallate - CAS 989-51-5 - Calbiochem Certificats d'analyse
Titre | Numéro de lot |
---|---|
324880 |
Références bibliographiques
Aperçu de la référence bibliographique |
---|
Choi, K.C., et al. 2009. Cancer Res. 69, 583. Dell'Aicia, I., et al. 2004. EMBO reports 5, 1. Tachibana, H., et al. 2004. Nat. Struct. Mol. Biol. 11, 380. Naasami, I., et al. 1998. Biochem. Biophys. Res. Commun. 249, 391. Ahmad, N., et al. 1997. J. Natl. Cancer 89, 1881. Chan, M.M.-Y., et al. 1997. Biochem. Pharmacol. 54, 1281. Lin, Y.-L., and Lin, J.-K. 1997. Mol. Pharmacol. 52, 465. Fiala, E.S., et al. 1996. Experientia 52, 922. Katiyar, S.K., et al. 1995. J. Invest. Dermatol. 105, 394. Liao, S., et al. 1995. Cancer Lett. 96, 239. Yamane, T., et al. 1995. Cancer Res. 55, 2081. Huang, M.T., et al. 1992. Carcinogenesis 13, 947. |
Brochure
Titre |
---|
Caspases and other Apoptosis Related Tools Brochure |