New Merck Products Bring Ease of Use to Single-Use

• Launching products at INTERPHEX 2016 include 1000-liter bioreactor for greater flexibility and continuity for scale-up
• 2000-liter mixer for difficult-to-mix buffers and media
• Large volume transport system for aseptic and non-aseptic liquids

Darmstadt, Germany, April 27, 2016 — Merck, a leading science and technology company, is launching three Mobius® products that deliver improved efficiency and ease-of-use for biopharmaceutical manufacturing workflows.

The new Mobius® products include a 1000-liter single-use bioreactor with an industry-leading design, a 2000-liter mixing system for difficult-to-mix biopharm ingredients and a large volume liquid transport system for aseptic and non-aseptic substances. “Our newest Mobius® products meet our customers’ increasingly complex demands for user friendly systems that allow them to focus on their science,” said Udit Batra, CEO, Life Science at Merck.

The Mobius® 1000 liter single-use bioreactor completes the comprehensive Mobius® stirred tank portfolio of 3 to 2000 liter sizes, delivering greater flexibility and continuity for scale-up. With the industry’s only bottom-loading drawer for easy and safe bag installation, Merck’s new bioreactor is designed to achieve homogenous and fast mixing for consistent performance, especially at large scale.

The Mobius® Power MIX 2000 creates a strong vortex to handle difficult-to-mix buffers, media and other biopharm ingredients. Powerful mixing is achieved from an impeller design and motor based on magnetically-coupled NovAseptic® technology, a proven mixing technology in stainless steel tanks. The Power MIX 2000 provides accessible, sterile zero deadleg sampling directly from the mixing container. A Probe Port allows insertion of either a reusable standard probe for non-aseptic processes or a pre-sterilized, single-use sensor for in-process pH measurement of aseptic processes.

The Mobius® single-use 3D large liquid transportation system’s single-use bags and stainless steel transporter bins facilitate the safe and convenient road transport of aseptic and nonaseptic media, buffers, in-process intermediates and final bulk drug products at cold or ambient temperatures. The system offers four single-use bag assemblies with working volumes of 100 to 500 liters. All bags are constructed from PureFlex™ Plus film with a proven low extractable profile and gas barrier properties.

Merck will showcase its industry-leading portfolio of single-use and other biopharmaceutical manufacturing products at booth #2841 at INTERPHEX 2016 in New York City from April 26 – 28. Follow us on Twitter @merckgroup.

About Merck
Merck is a leading science and technology company in healthcare, life science and performance materials. Around 50,000 employees work to further develop technologies that improve and enhance life – from biopharmaceutical therapies to treat cancer or multiple sclerosis, cutting-edge systems for scientific research and production, to liquid crystals for smartphones and LCD televisions. In 2015, Merck generated sales of €12.85 billion in 66 countries.

Founded in 1668, Merck is the world's oldest pharmaceutical and chemical company. The founding family remains the majority owner of the publicly listed corporate group. Merck, Darmstadt, Germany holds the global rights to the Merck name and brand. The only exceptions are the United States and Canada, where the company operates as EMD Serono, MilliporeSigma and EMD Performance Materials.