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598226 Thiostrepton - CAS 1393-48-2 - Calbiochem

598226
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Overview

Key Spec Table

CAS #Empirical Formula
1393-48-2C₇₂H₈₅N₁₉O₁₈S₅

Products

Catalogue NumberPackaging Qty/Pack
598226-10GM Glass bottle 10 gm
598226-1GM Plastic ampoule 1 gm
Description
OverviewA thiazole-containing peptide antibiotic that inhibits protein synthesis by preventing binding of GTP to 50S ribosomal subunit. Inhibits the function of elongation factor G (EF-G) and the dissociation of EF-G from the ribosome. The thiostrepton-resistant gene is also commonly used as a selective marker for recombinant DNA/plasmid technologies.
Catalogue Number598226
Brand Family Calbiochem®
SynonymsFOXM1 Inhibitor I
References
ReferencesRodnina, M.V., et al. 1999. Proc. Natl. Acad. Sci USA 96, 9586.
Rosendahl, G. and Douthwaite, S. 1994. Nucleic Acids Res. 22, 357.
Saarma, U. and Remme, J. 1992. Nucleic Acids Res. 20, 3147.
Malina, H. and Robert-Gero, M. 1992. Appl. Environ. Microbiol. 58, 895.
Blanco, G., et al. 1992. Gene 112, 59.
Miller, S.P. and Bodley, J.W. 1991. Nucleic Acids Res. 19, 1657.
Ryan, P.C., et al. 1991. J. Mol. Biol. 221, 1257.
Kutay, U.R., et al. 1990. Biochim. Biophys. Acta 1050, 193.
Smokvina, T., et al. 1990. Gene 94, 53.
Garrett, R. 1983. Trends Biochem. Sci. 8, 189.
Bodley, J.W., et al. 1970. Biochem. Biophys. Res. Commun. 41, 1406.
Thompson, J. and Cundliffe, E. 1970. Biochimie 73, 1131.
Product Information
CAS number1393-48-2
FormOff-white powder
Hill FormulaC₇₂H₈₅N₁₉O₁₈S₅
Chemical formulaC₇₂H₈₅N₁₉O₁₈S₅
Quality LevelMQ100
Biological Information
Primary TargetEF-G
Purity≥98% by HPLC
Safety Information according to GHS
RTECSXN6300100
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
598226-10GM 04055977189162
598226-1GM 07790788051914