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GF313 TGF- α Protein, Human Recombinant Animal Free

Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor & stimulates the proliferation of a wide range of epidermal & epithelial cells. Manufactured using all non-animal reagents.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P01135 Entrez Gene Number: NM_001099691.1, NM_003236.2
GF313
100 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

SourcePurity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF313
DescriptionTGF- α Protein, Human Recombinant Animal Free
Alternate Names
  • Transforming growth factor alpha
  • TGFa
  • TGF alpha
  • EGF-like TGF
  • TGF type 1
Background InformationTransforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
References
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationTransforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor & stimulates the proliferation of a wide range of epidermal & epithelial cells. Manufactured using all non-animal reagents.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli
Cross ReactivityChicken, Mouse, Rat
Entrez Gene Number
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF313 04053252691492

Documentation

TGF- α Protein, Human Recombinant Animal Free SDS

Title

Safety Data Sheet (SDS) 

TGF- α Protein, Human Recombinant Animal Free Certificates of Analysis

TitleLot Number
Recombinant Animal Free -2537452 2537452
Recombinant Animal Free -2721519 2721519
Recombinant Animal Free Human TGF- #945; - Q2007166 Q2007166
Recombinant Animal Free Human TGF- α - 3192463 3192463
Recombinant Animal Free Human TGF- α - 3351207 3351207
Recombinant Animal Free Human TGF- α - 3498489 3498489
Recombinant Animal Free Human TGF- α - 3601701 3601701
Recombinant Animal Free Human TGF- α - 3761065 3761065
Recombinant Animal Free Human TGF- α - 3781050 3781050
Recombinant Animal Free Human TGF- α - 3850545 3850545
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Brochure

Title
New Products: Volume 3, 2012

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