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GF317 TGF-β-III Protein, Human Recombinant Animal Free

TGF-β-III is one of three closely related mammalian members of the large TGF-β superfamily.Recombinant animal free human TGF-β-III is manufactured using all non-animal reagents.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P10600 Entrez Gene Number: 7043
GF317
10µg  
Purchase on Sigma-Aldrich

Overview

Key Spec Table

SourcePurity
E. coli.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses.
Description
Catalogue NumberGF317
DescriptionTGF-β-III Protein, Human Recombinant Animal Free
Alternate Names
  • Transforming Growth Factor Beta 3
  • TGF-Beta-3
  • TGF-Beta-III
Background InformationTGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily. TGF-β-I, TGF-β-II and TGF-β-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-β3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-β-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationTGF-β-III is one of three closely related mammalian members of the large TGF-β superfamily.Recombinant animal free human TGF-β-III is manufactured using all non-animal reagents.
Biological Information
PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses.
SourceE. coli.
Entrez Gene Number
UniProt Number
Product Usage Statements
Quality AssuranceDetermined by TGF-β-III’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size10µg
Global Trade Item Number
Catalogue Number GTIN
GF317 04053252599682