Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

528240 Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets

528240
Purchase on Sigma-Aldrich

Overview

Products

Catalogue NumberPackaging Qty/Pack
528240-1MG Plastic ampoule 1 mg
Description
OverviewNative, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds to fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα and GPIIbβ, whereas GPIIIa has only one polypeptide chain.
Catalogue Number528240
Brand Family Calbiochem®
SynonymsGPIIbIIIa, Fibrinogen Receptor, CD41/CD61
References
ReferencesSchwarz M., et al. 2004. J. Pharmacol. Exp. Therap. 308, 1002.
Wippler, J., et al. 1994. J. Biol. Chem. 269, 8754.
Product Information
FormLiquid
FormulationIn 100 mM NaCl, 20 mM Tris-HCl, 1 mM CaCl₂, 50% glycerol, ≤0.1% sodium azide, pH 7.4.
Quality LevelMQ100
Biological Information
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label Please refer to vial label for lot-specific concentration
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Avoid freeze/thaw cycles.
Global Trade Item Number
Catalogue Number GTIN
528240-1MG 04055977196535