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580556 Paclitaxel, Semi-Synthetic - CAS 33069-62-4 - Calbiochem

A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Promotes assembly of microtubules and inhibits tubulin disassembly.
580556
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Overview

Key Spec Table

CAS #Empirical Formula
33069-62-4C₄₇H₅₁NO₁₄

Products

Catalogue NumberPackaging Qty/Pack
580556-5MG Plastic ampoule 5 mg
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Description
OverviewA semi-synthetic form of Paclitaxel (Cat. No. 580555) having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.
Catalogue Number580556
Brand Family Calbiochem®
References
ReferencesDerry, W.B., et al. 1995. Biochemistry 34, 2203.
Milas, L., et al. 1995. Cancer Chemother. Pharmacol. 35, 297.
Donaldson, K.L., et al. 1994. Int. J. Cancer 57, 847.
Hornback, N.B., et al. 1994. In Vivo 8, 819.
Manthey, C.L., et al. 1992. J. Immunol. 149, 2459.
Rowinsky, E.K., et al. 1992. Semin. Oncol.19, 646.
Ding, A.H., et al. 1990. Science 248, 370.
Mogensen, M.M. and Tucker, J.B. 1990. J. Cell Sci. 97, 101.
Slichenmeyer, W.J. and Von Hoff, D.D. 1990. J. Clin. Pharmacol. 30, 770.
Product Information
CAS number33069-62-4
ATP CompetitiveN
FormCrystalline solid
Hill FormulaC₄₇H₅₁NO₁₄
Chemical formulaC₄₇H₅₁NO₁₄
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetPromotes assembly of microtubules and inhibits tubulin disassembly.
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Safety Information according to GHS
RTECSDA8340700
Safety Information
R PhraseR: 37/38-41-46-60

Irritating to respiratory system and skin.
Risk of serious damage to eyes.
May cause heritable genetic damage.
May impair fertility.
S PhraseS: 22-26-36/37/39-45

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Global Trade Item Number
Catalogue Number GTIN
580556-5MG 04055977265538