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Buffer Detection Kit for Magnetic Beads
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203995
Sigma-AldrichN-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem
Most commonly-used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
Catalogue Number
203995
Brand Family
Calbiochem®
Synonyms
PBN
References
References
Floyd, R.A. 1997. Adv. Pharmacol. 38, 361. Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114. Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam. Floyd, R.A. 1990. FASEB J. 4, 2587.
Following reconstitution in DMSO aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 2 months at -20°C. Unstable in aqueous solution; reconstitute just prior to use.
Global Trade Item Number
Catalogue Number
GTIN
203995-500MG
04055977220018
Documentation
N-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem SDS
N-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem Certificates of Analysis
Title
Lot Number
203995
References
Reference overview
Floyd, R.A. 1997. Adv. Pharmacol. 38, 361. Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114. Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam. Floyd, R.A. 1990. FASEB J. 4, 2587.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
22-May-2008 RFH
Synonyms
PBN
Description
Most commonly used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative diseases. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
Form
White solid
CAS number
3376-24-7
Chemical formula
C₁₁H₁₅NO
Structure formula
Purity
≥98% by GC
Solubility
DMSO (10 mg/ml), H₂O (20 mg/ml), or Chloroform (50 mg/ml)
Storage
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution in DMSO aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 2 months at -20°C. Unstable in aqueous solution; reconstitute just prior to use.
Toxicity
Standard Handling
References
Floyd, R.A. 1997. Adv. Pharmacol. 38, 361. Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114. Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam. Floyd, R.A. 1990. FASEB J. 4, 2587.
