Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

HAGP1MAG-12K MILLIPLEX MAP Human Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay

Angiogenesie Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Category: Cancer
HAGP1MAG-12K
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
Angiopoietin-2 BMP-9 EGF Endoglin Endothelin-1 FGF-1 FGF-2 Follistatin G-CSF HB-EGF HGF IL-8 Leptin PLGF VEGF-A VEGF-C VEGF-D HMplexLuminex xMAP
Description
Catalogue NumberHAGP1MAG-12K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Human Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay
OverviewMILLIPLEX® MAP Human Angiogenesis / Growth Factor Magnetic Bead Panel 1 enables you to focus on your angiogenesis / vascular research. Coupled with the Luminex® xMAP® platform in a magnetic bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, which can dramatically improve productivity.
Background InformationAngiogenesis, the development of new vascular networks, is a key process in normal growth and development as well as in wound healing, with homeostasis maintained by a delicate balance of angiogenic factors and inhibitors. Consequently, insufficient or excessive blood vessel growth underlies many diseases, including cardiovascular disease, diabetic ulcers, macular degeneration and cancer. Angiogenesis plays a significant role in tumor growth and metastasis.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra Assay: < 15
  • Inter Assay: < 5
Panel TypeMAGNETIC Circulating Cancer
Quality LevelMQ200
Applications
ApplicationAngiogenesie Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples.
Key Applications
  • Multiplexing
Application Notes• This is an overnight incubation assay requiring 25 µL of 1:3 dilution plasma or serum, or 25 μL cell culture supernatant per well.
• This kit may be used for the analysis of all or any combination of the cancer biomarkers in serum, plasma or tissue/cell lysate and culture supernatant

Biological Information
Species Reactivity
  • Human
Analytes Available
  • Angiopoietin-2
  • BMP-9
  • EGF
  • Endoglin
  • Endothelin-1
  • FGF-1
  • FGF-2
  • Follistatin
  • G-CSF
  • HB-EGF
  • HGF
  • IL-8
  • Leptin
  • PLGF
  • VEGF-A
  • VEGF-C
  • VEGF-D
Assay PanelEverything you need in a single kit.
Cross ReactivityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Accuracy
  • 42% - 131%
Physicochemical Information
Sensitivity
  • Refer to kit protocol for sensitivities of individual analytes.
Standard Curve Range
  • 13.7 - 10,000 pg/mL: Angiopoietin-2, FGF-1, FGF-2, G-CSF, VEGF-A
  • 2.7 - 2,000 pg/mL: BMP-9, EGF, Endothelin-1
  • 27.4 - 20,000 pg/mL: Endoglin, Follistatin, HGF
  • 1.4 - 1,000 pg/mL: HB-EGF, IL-8, PLGF
  • 137.2 - 100,000 pg/mL: Leptin
  • 6.9 - 5,000 pg/mL: VEGF-C, VEGF-D
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
HAGP1MAG-12K 04053252988400

Documentation

Protocols

Title
Protocol- HAGP1MAG-12K

MILLIPLEX MAP Human Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay SDS

Title

Safety Data Sheet (SDS) 

Brochure

Title
The Power of Biomarker Analysis

Technical Info

Title
96 well Template 2 Up
96 well Template Single
HAGP1MAG-12K xPonent Protocol Template Version 3.1
HAGP1MAG-12K xPonent Protocol Template Version Magpix
Quality Control Range Sheet- HAGG1-113 and HAGG1-213
Quality Control Ranges: Human Angiogenesis/ Growth Factor Magnetic Bead Panel 1
White Paper - Correlation of angiogenesis biomarkers with early metastatic progression in NSCLC

Posters

Title
Utility of human and mouse multiplex immunoassay panels for studying profiles of circulating angiogenic factors as biomarkers for angiogenesis research

Newsletters / Publications

Title
Article: Detection and localization of surgically resectable cancers with a multi-analyte blood test