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341600 Fibrinogen, Fragment D, Human Plasma

341600
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Overview

Products

Catalogue NumberPackaging Qty/Pack
341600-200UG Plastic ampoule 200 μg
Description
OverviewNative fibrinogen fragment D from human plasma prepared by plasmin digestion of purified fibrinogen followed by preparative electrophoresis. Thermolabile core fragment of fibrinogen. Complete proteolysis of a single fibrinogen molecule produces two D and one E fragments. The D and E fragments have no common antigenic determinants; therefore, no cross-reaction occurs. Reported to increase endothelial membrane permeability to albumin.
Catalogue Number341600
Brand Family Calbiochem®
References
ReferencesSpraggon, G., et al. 1997. Nature 389, 455.
Stirk, C.M., et al. 1993. Atherosclerosis 103, 159.
Vogel, P., et al. 1993. Eur. Surg. Res. 25, 83.
Azpiazu, I., and Chapman, D. 1992. Biochim. Biophys. Acta 1119, 268.
Thompson, W.D., et al. 1992. J. Pathol. 168, 47.
Fisher, E.G., et al. 1991. Haemostasis 21, 141.
Ge, M., et al. 1991. Am. J. Physiol. 261, L283.
Product Information
FormLyophilized
FormulationLyophilized from 400 mM glycine, 150 mM NaCl.
Quality LevelMQ200
Applications
ApplicationFibrinogen fragment D is a thermolabile native human plasma protein prepared by digestion of purified fibrinogen followed by preparative electrophoresis.
Biological Information
Puritysingle band by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
ContaminantsFragment E: ≤1%
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 4 h at 20°C or for up to 8 h at 4°C or for up to 3 months at -70°C.
Global Trade Item Number
Catalogue Number GTIN
341600-200UG 04055977195187