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14-473 Fes/Fps Protein, active, 10 µg

14-473
10 µg  Also available in 250 µg size --call for pricing and availability and reference catalog number 14-473M when ordering the 250 µg size.
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-473
Brand Family Upstate
Trade Name
  • Upstate
DescriptionFes/Fps Protein, active, 10 µg
OverviewRecombinant full length human Fes, containing an N-terminal His6-tag
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, recombinant full length human Fes, containing an N-terminal His6-tag, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceExpressed by baculovirus in Sf21 insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryThis gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.
Gene Symbol
  • FES
  • FPS
  • C-Fes
Protein TargetFes/Fps
Purification MethodNi-NTA agarose
Target Sub-FamilyTK
UniProt Number
UniProt SummarySIZE: 822 amino acids; 93497 Da
SIMILARITY: SwissProt: P07332 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. & Contains 1 FCH domain. & Contains 1 protein kinase domain. & Contains 1 SH2 domain.
Molecular Weight98kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of the Poly (Glu4-Tyr) (4:1) substrate
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions1 year at -70C
Packaging Information
Material Size10 µg
Material PackageAlso available in 250 µg size --call for pricing and availability and reference catalog number 14-473M when ordering the 250 µg size.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-473 04053252621659

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-473M Fes/Fps Protein, active, 250 µg

Product Families

Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases