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S8005H CpGenome™ 5-hmC DNA Standard

CpGenome 5-hmC DNA St&ard contains a linear, double-str&ed DNA (897 bp) with 100 % hydroxymethylated cytosine. This st&ard can be used to calibrate applications aimed at analyzing & quantifying cytosine modifications.

CpGenome™ 5-hmC DNA Standard MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
S8005H
2 µg per vial  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberS8005H
Brand Family Upstate
Trade Name
  • CpGenome
  • Upstate
DescriptionCpGenome™ 5-hmC DNA Standard
OverviewCpGenome™ 5-hmC DNA Standard is a linear, double-stranded DNA (897 bp) containing 100% 5-hydroxymethylcytosine. This standard can be used to calibrate applications aimed at analyzing and quantifying cytosine modifications. This vial is a component of S8005 the CpGenome™ 5-mC and 5-hmC DNA Standard Set ( three linear, double-stranded DNAs (897 bp) with the same sequence, but containing either 100% 5-Methylcytosines (5-mC), 5-hydroxymethylcytosines (5-hmC), or unmodified cytosines.

Materials Provided:

One vial containing 2 µg (40 µL) of CpGenome™ 5-hmC DNA Standard at a concentration of 50 ng/μL.

Validation:

Standards containing either 5-mC, 5-hmC, or unmodified cytosines were digested with 1 µL (20 units) of HpaII (which cleaves only unmethylated DNA), or PvuRts1I restriction enzyme (which targets only 5-hydroxymethylated DNA). The resulting DNA fragments were evaluated by agarose gel electrophoresis.

CpGenome is a trademark of Serologicals Corporation.
References
Product Information
PresentationLiquid in buffer containing 10 mM Tris-HCl, 1 mM EDTA, pH 8.0
Quality LevelMQ100
Applications
ApplicationCpGenome 5-hmC DNA St&ard contains a linear, double-str&ed DNA (897 bp) with 100 % hydroxymethylated cytosine. This st&ard can be used to calibrate applications aimed at analyzing & quantifying cytosine modifications.
Biological Information
Species Reactivity
  • Human
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended Storage: Stable for 6 months at -20°C from date of receipt.
Packaging Information
Material Size2 µg per vial
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
S8005H 04053252908934

Documentation

CpGenome™ 5-hmC DNA Standard SDS

Title

Safety Data Sheet (SDS) 

CpGenome™ 5-hmC DNA Standard Certificates of Analysis

TitleLot Number
CpGenome 5-hmC DNA Standard - Q2193410 Q2193410
CpGenome™ 5-hmC DNA Standard - 3216483 3216483
CpGenome™ 5-hmC DNA Standard - 3496502 3496502
CpGenome™ 5-hmC DNA Standard - 3824792 3824792
CpGenome™ 5-hmC DNA Standard - 3906943 3906943
CpGenome™ 5-hmC DNA Standard - 4053089 4053089
CpGenome™ 5-hmC DNA Standard -2794482 2794482
CpGenome™ 5-hmC DNA Standard - 2462920 2462920

Brochure

Title
Shaping Epigenetics Discovery - DNA Methylation Brochure

Technical Info

Title
White Paper - The Message in the Marks: Deciphering Cancer Epigenetics