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218728 Caspase-9 Inhibitor III - CAS 403848-57-7 - Calbiochem

218728
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Overview

Key Spec Table

CAS #Empirical Formula
403848-57-7C₂₄H₃₅ClN₆O₉

Products

Catalogue NumberPackaging Qty/Pack
218728-1MG Plastic ampoule 1 mg
Description
OverviewA potent, irreversible inhibitor of caspase-9. Reported to reduce myocardial infarct size during reperfusion (~70 nM).
Catalogue Number218728
Brand Family Calbiochem®
SynonymsAc-LEHD-CMK
References
ReferencesMocanu, M.M., et al. 2000. Br. J. Pharmacol. 130, 197.
Product Information
CAS number403848-57-7
ATP CompetitiveN
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₂₄H₃₅ClN₆O₉
Chemical formulaC₂₄H₃₅ClN₆O₉
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary Targetcaspase-9
Primary Target IC<sub>50</sub>70 nM against caspase-9
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceAc-Leu-Glu-His-Asp-CMK
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
218728-1MG 07790788048594