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SCT211 BioTracker Green Sulfane Sulfur live cell dye

Live Cell imaging probe for sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-Sn-S-R) and ploysulfide (H2Sn).

SCT211
3 x 60 nmol  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberSCT211
DescriptionBioTracker Green Sulfane Sulfur live cell dye
OverviewIntracellularly abundant sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-Sn-S-R) and polysulfide (H2Sn) play important roles to maintain intracellular reducing environments.

BioTracker Green Sulfane Sulfur Live Cell Dye is a FRET-based fluorescence probe to specifically detect the intracellular sulfane sulfur species. It shows only weak fluorescence without sulfane sulfur, and reversibly fluoresces in response to micromolar concentrations of sulfane sulfur. Its reaction is highly specific and has minimal to no reactivity with H2S, cysteine residues, and sulfur oxides. The dye is a cell permeable diacetylated form which is hydrolyzed by intracellular esterases to generate a metabolite which is retained within the cells. Thus it is suitable to monitor intracellular concentration of sulfane sulfur via live-cell imaging.

Spectral Properties
Absorbance (max): 495nm
Emission (max): 525nm

References
Takano Y et al. Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application. Chem Commun. 2017. Jan 17; 53(6):1064-1067.
Alternate Names
  • SSip-1 DA, 60 nmol x 3
References
Product Information
Detection methodFluorescence
PresentationLyophilized
Applications
ApplicationLive Cell imaging probe for sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-Sn-S-R) and ploysulfide (H2Sn).
Key Applications
  • Cell Based Assays
Application NotesLive cell fluorescent imaging. Green fluorescence.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssurancePurity: ≥ 65% (LC)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore BioTracker Green Sulfane Sulfur Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
Packaging Information
Material Size3 x 60 nmol
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
SCT211 04061841697633