189490 Sigma-AldrichAutophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem
Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis following serum/potassium deprivation.
More>> Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis following serum/potassium deprivation. Less<<Synonyms: 3-Methyladenine
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Overview
Key Spec Table
CAS # | Empirical Formula |
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5142-23-4 | C₆H₇N₅ |
Products
Catalogue Number | Packaging | Qty/Pack | |
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189490-100MG | Glass bottle | 100 mg | |
189490-50MG | Plastic ampoule | 50 mg |
Description | |
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Overview | A widely used cell-permeable autophagic sequestration blocker that effectly protects cerebellar granule cells from apoptosis following serum/potassium deprivation. Although a known class III PI3K inhibitor (IC50 = 4.5 mM in cell-free enzymatic assays), 3-MA exhibits quite distinct pharmacological properties from those of two other PI3K inhibitors, LY 294002 (Cat. Nos. 440202 and 440204) and Wortmannin (Cat. No. 681675) |
Catalogue Number | 189490 |
Brand Family | Calbiochem® |
Synonyms | 3-Methyladenine |
Product Information | |
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CAS number | 5142-23-4 |
Form | White to faint yellow powder |
Hill Formula | C₆H₇N₅ |
Chemical formula | C₆H₇N₅ |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Purity | ≥95% by HPLC |
Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Global Trade Item Number | |
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Catalogue Number | GTIN |
189490-100MG | 04055977221831 |
189490-50MG | 07790788048235 |