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07-1473 Anti-Phosphothreonine-Proline Antibody

Detect Phosphothreonine-Proline using this Anti-Phosphothreonine-Proline Antibody validated for use in WB.

Anti-Phosphothreonine-Proline Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: General Post-translation Modification
07-1473
100 µg  
Purchase on Sigma-Aldrich

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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue Number07-1473
ReplacesAB3192
DescriptionAnti-Phosphothreonine-Proline Antibody
Background InformationPhosphothreonine-Proline, along with similar motifs involving serine/threonine residues preceding proline undergoing phosphorylation, has critical roles in the moderation of various cellular processes, protein function, and kinases through proline-directed phosphorylation. The deregulation of proline-directed phosphorylation is known to be a factor in diseases such as cancer and Alzheimer’s neurodegeneration.
References
Product Information
FormatAffinity Purified
Control
  • Calyculin treated Jurkat cell lysate
PresentationLiquid in TBS with 0.05% sodium azide and 50% glycerol.
Quality LevelMQ100
Applications
ApplicationDetect Phosphothreonine-Proline using this Anti-Phosphothreonine-Proline Antibody validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-phosphothreonine-proline amide
(pT-P-NH2) peptide conjugates
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes the phosphorylated phothreonine-proline motif, which is the site of phosphorylation of many proline-directed protein kinase such MAPK and cyclin-dependent protein kinases. Also recognizes the phosphoserine-proline motif to a similar degree.
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Purification MethodAffinity Purfied
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in Calyculin treated Jurkat cell lysate.
Western Blot Analysis: 1:500 dilution of this lot detected phosphorylated proteins on 10 μg of calyculin treated Jurkat lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
07-1473 04053252584855

Documentation

Anti-Phosphothreonine-Proline Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Phosphothreonine-Proline Antibody Certificates of Analysis

TitleLot Number
Anti- Phosphothreonine-Proline - 2360880 2360880
Anti- Phosphothreonine-Proline - 2443061 2443061
Anti- Phosphothreonine-Proline - 2197310 2197310
Anti- Phosphothreonine-Proline - 3193340 3193340
Anti- Phosphothreonine-Proline - 3251465 3251465
Anti- Phosphothreonine-Proline - 3835300 3835300
Anti- Phosphothreonine-Proline - NRG1704138 NRG1704138
Anti- Phosphothreonine-Proline -2523900 2523900
Anti- Phosphothreonine-Proline Polyclonal Antibody 2971921