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AB15300 Anti-NECL-1 Antibody

Detect NECL-1 using this Anti-NECL-1 Antibody validated for use in IH & WB.

Anti-NECL-1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurofilament & Neuron Metabolism Gene Symbol: CADM3, IGSF4B, NECL1, SYNCAM3, TSLL1 UniProt Number: Q8N126
AB15300
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MIHC, WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB15300
Trade Name
  • Chemicon
DescriptionAnti-NECL-1 Antibody
Background InformationNectins are immunoglobulin superfamily adhesion molecules that participate in the organization of epithelial and endothelial junctions. Human and mouse NECL1 share 87.3% identity at the amino acid level (1). NECL1 contains an ectodomain made of three immunoglobulin-like domains, and a cytoplasmic region homologous to those of glycophorin C and contactin-associated protein. NECL1 predominantly expressed in the central nervous system, mainly in neuronal cell bodies in a variety of brain regions including the cerebellum, cerebral cortex and hippocampus. NECL1 localizes to the cell-cell junctions and recruits protein 4.1N to the plasma membranes through its C-terminus, thus may regulate the function of the cell-cell junction.
References
Product Information
FormatAffinity Purified
Control
  • Tested on Adult mouse brain lysate
PresentationPurified Antibody in PBS with 0.1% NaN3
Quality LevelMQ100
Applications
ApplicationDetect NECL-1 using this Anti-NECL-1 Antibody validated for use in IH & WB.
Key Applications
  • Immunohistochemistry
  • Western Blotting
Application NotesWestern Blot Analysis: NECL-1 can be detected at 1/500 dilution. Testing at further dilution was not conducted.

Immunohistochemistry: 1:50 to 1:1000 straight dilution of Cat. # AB15301 was tested on human medulla oblongata tissue.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic Peptide
HostRabbit
SpecificityNECL-1
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Gene Symbol
  • CADM3
  • IGSF4B
  • NECL1
  • SYNCAM3
  • TSLL1
Purification MethodImmunoAffinity Purified
UniProt Number
Molecular Weight43 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB15300 04053252589324