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AB9830-50UL Anti-K2P4.1 Antibody

AB9830-50UL
50 µL  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
RIHC, WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9830-50UL
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-K2P4.1 Antibody
Alternate Names
  • TRAAK
  • TWIK-related arachidonic acid-stimulated K+ channel
  • KCNK4
References
Product Information
FormatAffinity Purified
Control
  • Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
PresentationAffinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
Quality LevelMQ100
Applications
ApplicationAnti-K2P4.1 Antibody is an antibody against K2P4.1 for use in IH & WB.
Key Applications
  • Immunohistochemistry
  • Western Blotting
Application NotesWestern blot: 1:200 using ECL on rat cerebellum lysate and HEK- K2P4.1 transfected cells.
Immunohistochemistry on rat brain sections.
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenPurified peptide from amino acids 343-359 of human K2P4.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes K2P4.1 (TRAAK, TWIK-related arachidonic acid-stimulated K+ channel, KCNK4).
IsotypeIgG
Species Reactivity
  • Rat
Species Reactivity NoteThe immunogen sequence is identical in mouse, rat and canine.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryPotassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.
Gene Symbol
  • KCNK4
  • TRAAK
  • K2p4.1
  • TRAAK1
Purification MethodImmunoAffinity Purified
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q9NYG8 # Voltage insensitive, instantaneous, outwardly rectifying potassium channel. Outward rectification is reversed at high external K(+) concentrations (By similarity).
SIZE: 393 amino acids; 42704 Da
SUBUNIT: Homodimer (Potential).
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
SIMILARITY: SwissProt: Q9NYG8 ## Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB9830-50UL 04053252334962

Documentation

Anti-K2P4.1 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-K2P4.1 Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI-K2P4.1 (TRAAK) AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2445818 2445818
RABBIT ANTI-K2P4.1 (TRAAK) - 4104146 4104146
RABBIT ANTI-K2P4.1 (TRAAK) AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2068416 2068416
RABBIT ANTI-K2P4.1 (TRAAK) AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2295400 2295400

Data Sheet

Title
RABBIT ANTI-K2P4.1 (TRAAK) AFFINITY PURIFIED POLYCLONAL ANTIBODY