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ABE492 Anti-Histone lysine demethylase NO66 Antibody

Detect NO66 using this rabbit polyclonal antibody, Anti-Histone lysine demethylase NO66 Antibody validated for use in western blotting.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: NO66, C14orf169, MAPJD UniProt Number: Q9H6W3
ABE492
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE492
DescriptionAnti-Histone lysine demethylase NO66 Antibody
Alternate Names
  • Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
  • 60S ribosomal protein L8 histidine hydroxylase
  • Histone lysine demethylase NO66
  • Myc-associated protein with JmjC domain
  • Nucleolar protein 66
  • hsNO66
  • Ribosomal oxygenase NO66
  • ROX
  • NO66
Background InformationNO66 is a lysine-specific demethylase that removes methyl groups from histone H3 at lysine 4 and lysine 36. This enzyme has been shown to more readily demethylate trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 Lys4 (H3K4me1) consistent with its role in modulating the histone code. This protein is a highly conserved, constitutive nucleolar component that shows a dual localization pattern with strong enrichment in the granular part of nucleoli and in distinct nucleoplasmic entities.
References
Product Information
FormatAffinity Purified
Control
  • A431 cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect NO66 using this rabbit polyclonal antibody, Anti-Histone lysine demethylase NO66 Antibody validated for use in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Histone lysine demethylase NO66 near the N-terminus.
EpitopeNear N-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes Histone lysine demethylase NO66 near the N-terminus.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • NO66
  • C14orf169
  • MAPJD
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~66 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Histone lysine demethylase NO66 in 10 µg of A431 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABE492 04053252910814