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251700 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,5-DNS-GGACK, 2HCl

Primary Target: UPA
251700
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Overview

Products

Catalogue NumberPackaging Qty/Pack
251700-5MG Plastic ampoule 5 mg
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Description
OverviewEffective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
Catalogue Number251700
Brand Family Calbiochem®
Synonyms1,5-DNS-GGACK, 2HCl
References
ReferencesBajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
Product Information
ATP CompetitiveN
FormOff-white solid
ReversibleN
Quality LevelMQ100
Applications
Application1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.
Biological Information
Primary TargetUPA
Primary Target IC<sub>50</sub>100 nM for factor Xa
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Global Trade Item Number
Catalogue Number GTIN
251700-5MG 04055977217957