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679100 Vitamin D₂, 1α-Hydroxy- - CAS 54573-75-0 - Calbiochem

A vitamin D2 analog with potential for the treatment of secondary hyperparathyroidism and metabolic bone disease.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1α-OH-D₂

679100
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
54573-75-0C₂₈H₄₄O₂
Description
OverviewA vitamin D2 analog with potential for the treatment of secondary hyperparathyroidism and metabolic bone disease. May be an effective and safer alternative to Calcitriol (1α,25-Dihydroxyvitamin D3; Cat. No. 679101) for suppressing PTH without causing hypercalcemia. Metabolized in vivo to the natural active dihydroxylated metabolite of vitamin D2, 1α,25-dihydroxyvitamin D2.
Catalogue Number679100
Brand Family Calbiochem®
Synonyms1α-OH-D₂
References
ReferencesCoburn, J.W., et al. 1996. Nephrol. Dial. Transplant. 11 (Suppl. 3), 153.
Knutson, J.C., et al. 1995. Endocrinology 136, 4749.
Product Information
CAS number54573-75-0
FormWhite crystalline solid
Hill FormulaC₂₈H₄₄O₂
Chemical formulaC₂₈H₄₄O₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSVS2950000
Safety Information
R PhraseR: 28-63

Very toxic if swallowed.
Possible risk of harm to the unborn child.
S PhraseS: 22-36/37/39-45

Do not breathe dust.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Highly Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
679100 0

Documentation

Vitamin D₂, 1α-Hydroxy- - CAS 54573-75-0 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Vitamin D₂, 1α-Hydroxy- - CAS 54573-75-0 - Calbiochem Certificates of Analysis

TitleLot Number
679100

References

Reference overview
Coburn, J.W., et al. 1996. Nephrol. Dial. Transplant. 11 (Suppl. 3), 153.
Knutson, J.C., et al. 1995. Endocrinology 136, 4749.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-September-2008 RFH
Synonyms1α-OH-D₂
DescriptionVitamin D2 analog with potential for the treatment of secondary hyperparathyroidism and metabolic bone disease. May be an effective and safer alternative to calcitriol (1α,25-dihydroxyvitamin D3, Cat. No. 679101) for suppressing PTH without causing hypercalcemia. Metabolized in vivo to the natural active dihydroxylated metabolite to vitamin D2, 1α,25-dihydroxyvitamin D2.
FormWhite crystalline solid
Intert gas (Yes/No) Packaged under inert gas
CAS number54573-75-0
RTECSVS2950000
Chemical formulaC₂₈H₄₄O₂
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityEthanol
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
Toxicity Highly Toxic & Carcinogenic / Teratogenic
ReferencesCoburn, J.W., et al. 1996. Nephrol. Dial. Transplant. 11 (Suppl. 3), 153.
Knutson, J.C., et al. 1995. Endocrinology 136, 4749.