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677500 Vinpocetine

677500
  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
OverviewA cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE 1; IC50 = 20 µM). A cerebral vasodilator.
Catalogue Number677500
Brand Family Calbiochem®
References
ReferencesMolnar-Kimber, K., et al. 1993. Agents Actions 39, C77. Marley, P.D., and Thomson, K.A. 1992. Biochem. Pharmacol. 44, 2105. Yamaki, M., et al. 1992. Am. J. Physiol. 262, F957. Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331. Hagiwara, M., et al. 1984. Biochem. Pharmacol. 33, 453.
Product Information
CAS number42971-09-5
FormWhite solid
Hill FormulaC₂₂H₂₆N₂O₂
Chemical formulaC₂₂H₂₆N₂O₂
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetCa2+ -calmodulin-dependent phosphodiesterase
Primary Target IC<sub>50</sub>20 µM
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSJW4792000
Safety Information
R PhraseR: 22

Harmful if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
677500 0

Documentation

Vinpocetine Certificates of Analysis

TitleLot Number
677500

References

Reference overview
Molnar-Kimber, K., et al. 1993. Agents Actions 39, C77. Marley, P.D., and Thomson, K.A. 1992. Biochem. Pharmacol. 44, 2105. Yamaki, M., et al. 1992. Am. J. Physiol. 262, F957. Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331. Hagiwara, M., et al. 1984. Biochem. Pharmacol. 33, 453.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-May-2008 RFH
DescriptionA cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE 1; IC50 = 20 µM). Cerebral vasodilator.
FormWhite solid
CAS number42971-09-5
RTECSJW4792000
Chemical formulaC₂₂H₂₆N₂O₂
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityAcetone, Ethanol (10 mg/ml) or DMSO (5 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Harmful
Merck USA index14, 9991
ReferencesMolnar-Kimber, K., et al. 1993. Agents Actions 39, C77. Marley, P.D., and Thomson, K.A. 1992. Biochem. Pharmacol. 44, 2105. Yamaki, M., et al. 1992. Am. J. Physiol. 262, F957. Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331. Hagiwara, M., et al. 1984. Biochem. Pharmacol. 33, 453.