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673000 Vacuolin-1 - CAS 351986-85-1 - Calbiochem

A cell-permeable triazine based compound that inhibits Ca2+-dependent fusion of lysosomes with the plasma membrane and the release of lysosomal content, without affecting enlargeosomes or other membrane-bound organelles.

Vacuolin-1 - CAS 351986-85-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Ca2+-dependent fusion of lysosomes with the plasma membrane
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
351986-85-1C₂₆H₂₄IN₇O

Products

Catalogue NumberPackaging Qty/Pack
673000-10MG Glass bottle 10 mg
Description
OverviewA cell-permeable triazine based compound that inhibits Ca2+-dependent fusion of lysosomes with the plasma membrane and the release of lysosomal content, without affecting enlargeosomes or other membrane-bound organelles. It does not disturb the organization of the actin or tubulin cytoskeletal network, nor does it interfere with membrane traffic along the constitutive pathway from the ER to the plasma membrane.
Catalogue Number673000
Brand Family Calbiochem®
References
ReferencesCerny, J., et al. 2004. EMBO Rep. 5, 883.
Product Information
CAS number351986-85-1
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₆H₂₄IN₇O
Chemical formulaC₂₆H₂₄IN₇O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetCa2+-dependent fusion of lysosomes with the plasma membrane
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
673000-10MG 04055977183511

Documentation

Vacuolin-1 - CAS 351986-85-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Vacuolin-1 - CAS 351986-85-1 - Calbiochem Certificates of Analysis

TitleLot Number
673000

References

Reference overview
Cerny, J., et al. 2004. EMBO Rep. 5, 883.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-April-2011 RFH
DescriptionA cell-permeable triazine-based compound that inhibits Ca2+-dependent exocytosis of lysosomes induced by ionomycin or plasma membrane wounding. Does not affect the resealing process and the exocytosis of enlargeosomes. It also does not disturb the organization of the actin or tubulin cytoskeletal network or interfere with membrane traffic along the constitutive pathway from the ER to the plasma membrane.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number351986-85-1
Chemical formulaC₂₆H₂₄IN₇O
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesCerny, J., et al. 2004. EMBO Rep. 5, 883.