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676493 VEGF Inhibitor, Flt₂₋₁₁ - Calbiochem

The VEGF Inhibitor, Flt2-11 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

VEGF Inhibitor, Flt₂₋₁₁ - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NITVTLKKFPL, VEGFR Tyrosine Kinase Inhibitor X, VEGFR1 Kinase Inhibitor I

Primary Target: VEGF
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₆₁H₁₀₄N₁₄O₁₅

Products

Catalogue NumberPackaging Qty/Pack
676493-1MG Plastic ampoule 1 mg
Description
OverviewAn 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is shown to inhibit angiogenesis in chick chorioallantoic membrane and inhibits VEGF-induced vascular permeability. Neither binds to vascular endothelial growth factor (VEGF) nor inhibits its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution.
Catalogue Number676493
Brand Family Calbiochem®
SynonymsNITVTLKKFPL, VEGFR Tyrosine Kinase Inhibitor X, VEGFR1 Kinase Inhibitor I
References
ReferencesTan, D.C., et al. 2001. FEBS Lett. 494, 150.
Product Information
ATP CompetitiveN
DeclarationSold under license of U.S. Patent 6,200,954.
FormWhite lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₆₁H₁₀₄N₁₄O₁₅
Chemical formulaC₆₁H₁₀₄N₁₄O₁₅
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetVEGF
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceH-Asn-Ile-Thr-Val-Thr-Leu-Lys-Lys-Phe-Pro-Leu-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
676493-1MG 04055977183696

Documentation

VEGF Inhibitor, Flt₂₋₁₁ - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

VEGF Inhibitor, Flt₂₋₁₁ - Calbiochem Certificates of Analysis

TitleLot Number
676493

References

Reference overview
Tan, D.C., et al. 2001. FEBS Lett. 494, 150.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-September-2008 RFH
SynonymsNITVTLKKFPL, VEGFR Tyrosine Kinase Inhibitor X, VEGFR1 Kinase Inhibitor I
DescriptionAn 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is reported to inhibit angiogenesis in chick chorioallantoic membrane and VEGF-induced vascular permeability. Does not bind to vascular endothelial growth factor (VEGF) nor inhibit its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution.
FormWhite lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₆₁H₁₀₄N₁₄O₁₅
Peptide SequenceH-Asn-Ile-Thr-Val-Thr-Leu-Lys-Lys-Phe-Pro-Leu-OH
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml) or acetonitrile (20%)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesTan, D.C., et al. 2001. FEBS Lett. 494, 150.