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14-632M TSSK2 Protein, active, 250 µg

14-632M
250 µg  Also available in 10 μg size (cat#14-632) and in bulk (cat#14-632-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-632M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionTSSK2 Protein, active, 250 µg
OverviewN-terminal His6-tagged, recombinant, full length, human TSSK2, expressed by baculovirus in Sf21 insect cells
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal His6-tagged, recombinant, full length, human TSSK2, expressed by baculovirus in Sf21 insect cells, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourcefull length, human TSSK2
Entrez Gene Number
Entrez Gene SummaryTSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM]
Gene Symbol
  • TSSK2
  • FLJ38613
  • DGSG
  • SPOGA2
  • TSK-2
  • STK22B
  • DGS-G
Protein TargetTSSK2
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyCAMK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q96PF2 # Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm (By similarity).
COFACTOR: Magnesium (By similarity).
SIZE: 358 amino acids; 40939 Da
SUBUNIT: Binds to STK22A (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Testis.
PTM: Autophosphorylated (By similarity).
DISEASE: SwissProt: Q96PF2 # May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).
SIMILARITY: SwissProt: Q96PF2 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
Molecular Weight44.8kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of CHKtide
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-632) and in bulk (cat#14-632-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-632M 04053252924453

Documentation

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-632 TSSK2 Protein, active, 10 µg

Product Families

Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases