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616455 Sigma-AldrichTGF-β1, Human, Recombinant, CHO Cell Line

TGF-β1, Human, Recombinant, CHO Cell Line MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA
References
Data Sheet

Synonyms: rhTGF-β1, Transforming Growth Factor-β1

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Overview

Replacement Information

Key Spec Table

Purity
≥97% by SDS-PAGE

Description
Overview	This product has been discontinued. Recombinant, human transforming growth factor-β1 expressed in CHO cells. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells. Induces the accumulation of extracellular matrix in various diseases.
Catalogue Number	616455
Brand Family	Calbiochem®
Synonyms	rhTGF-β1, Transforming Growth Factor-β1

References
References	Shibuya, H., et al. 1996. Science 272, 1179. Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA 93, 5877. Lomo, J., et al. 1995. J. Immunol. 154, 1634. Marushige, K., and Marushige, Y. 1995. Anticancer Res. 14, 2419. Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.

Product Information
Form	Lyophilized
Formulation	Lyophilized from a sterile filtered solution in 50 µg BSA/µg TGF-β1, 35% acetonitrile, 0.1% TFA.
Quality Level	MQ100

Applications

Biological Information
Biological activity	ED₅₀ = 0.04-0.1 ng/ml
Purity	≥97% by SDS-PAGE

Physicochemical Information
Contaminants	Endotoxin: ≤1 EU/µg TGF-β1

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
Catalogue Number	GTIN
616455	0

Documentation

TGF-β1, Human, Recombinant, CHO Cell Line SDS

Title
Safety Data Sheet (SDS)

TGF-β1, Human, Recombinant, CHO Cell Line Certificates of Analysis

Title	Lot Number
616455	Enter Lot Number

References

Reference overview
Shibuya, H., et al. 1996. Science 272, 1179. Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA 93, 5877. Lomo, J., et al. 1995. J. Immunol. 154, 1634. Marushige, K., and Marushige, Y. 1995. Anticancer Res. 14, 2419. Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	19-May-2008 RFH
Synonyms	rhTGF-β1, Transforming Growth Factor-β1
Description	Recombinant, human transforming growth factor-β1 expressed in CHO cells. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells. Induces the accumulation of extracellular matrix in various diseases.
Form	Lyophilized
Formulation	Lyophilized from a sterile filtered solution in 50 µg BSA/µg TGF-β1, 35% acetonitrile, 0.1% TFA.
Purity	≥97% by SDS-PAGE
Contaminants	Endotoxin: ≤1 EU/µg TGF-β1
Biological activity	ED₅₀ = 0.04-0.1 ng/ml
Solubility	Reconstitute to a concentration ≥1 µg/ml in 4 mM sterile HCl containing ≥0.1% HSA or BSA.
Storage	-20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
Merck USA index	14, 9572
References	Shibuya, H., et al. 1996. Science 272, 1179. Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA 93, 5877. Lomo, J., et al. 1995. J. Immunol. 154, 1634. Marushige, K., and Marushige, Y. 1995. Anticancer Res. 14, 2419. Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.

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