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568500 SQ 22536 - CAS 17318-31-9 - Calbiochem

Cell-permeable adenylate cyclase inhibitor.

SQ 22536 - CAS 17318-31-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 9-(Tetrahydro-2ʹ-furyl)adenine

Primary Target: adenylate cyclase
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
17318-31-9C₉H₁₁N₅O

Products

Catalogue NumberPackaging Qty/Pack
568500-5MG Glass bottle 5 mg
Description
OverviewCell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC50 = 200 µM). Reduces PGE2-induced inhibition of O2·– production.
Catalogue Number568500
Brand Family Calbiochem®
Synonyms9-(Tetrahydro-2ʹ-furyl)adenine
References
ReferencesTalpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
Tamaoki, J., et al. 1993. Prostaglandins 45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib. 5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.
Product Information
CAS number17318-31-9
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₉H₁₁N₅O
Chemical formulaC₉H₁₁N₅O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetadenylate cyclase
Primary Target IC<sub>50</sub>200 µM against adenylate cyclase
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
568500-5MG 04055977190397

Documentation

SQ 22536 - CAS 17318-31-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

SQ 22536 - CAS 17318-31-9 - Calbiochem Certificates of Analysis

TitleLot Number
568500

References

Reference overview
Talpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
Tamaoki, J., et al. 1993. Prostaglandins 45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib. 5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.

Brochure

Title
Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2008 RFH
Synonyms9-(Tetrahydro-2ʹ-furyl)adenine
DescriptionCell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC50 = 200 µM). Reduces PGE2-induced inhibition of O2·– production.
FormOff-white solid
CAS number17318-31-9
Chemical formulaC₉H₁₁N₅O
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (25 mg/ml) or H₂O (5 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.
Toxicity Irritant
ReferencesTalpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
Tamaoki, J., et al. 1993. Prostaglandins 45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib. 5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.