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03-0125-01 SMC™ Mouse IL-17F Discovery Immunoassay Kit

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03-0125-01
96 well assay  
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Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey Applications
IL-17F MSingle Molecule Counting (SMC®)
Description
Catalogue Number03-0125-01
Trade Name
  • SMC®
DescriptionSMC™ Mouse IL-17F Discovery Immunoassay Kit
OverviewThe SMC™ Mouse IL-17F Discovery Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology.
Background InformationInterleukin-17F (IL-17F) is a member of a group of cytokines called the IL-17 family. Other members in the family include IL-17A, IL-17B, IL-17C and IL-17E (IL-17E is also known as IL-25). IL-17F is involved in mediating pro-inflammatory responses by inducing the production of many other cytokines, chemokines, and prostaglandins from many cell types. The increased expression of chemokines attracts other cells, including neutrophils. IL-17F has many physiological functions, such as airway remodeling. As a result of these roles, the IL-17 family has been linked to many immune/autoimmune related diseases, including rheumatoid arthritis (RA), asthma, allergic responses, lupus, allograft rejection and anti-tumor immunity.
References
Product Information
Components
  • Assay Buffer
  • Mouse IL-17F Coating Antibody
  • Assay Plate
  • 10X PBS
  • Blocking Buffer
  • Standard Diluent
  • Mouse IL-17F Detection Antibody
  • Mouse IL-17F Standard
  • SMC™ Mouse IL-17F Immunoassay Kit Instructions
  • 10X Wash Buffer
  • Buffer C
  • Elution Buffer B
Precision, %
  • Low-end CV% Range: 3-9%
  • Low-end CV% Average: 5%
Quality LevelMQ200
Applications
ApplicationThe sensitivity of Single Molecule Counting (SMC™) technology gives the SMC™ Mouse IL-17F Discovery Immunoassay unparalleled performance in the quantification of IL-17F in mouse serum.
Key Applications
  • Single Molecule Counting (SMC®)
Biological Information
Species Reactivity
  • Mouse
Analytes Available
  • IL-17F
Accuracy
  • Minimum of 10 samples spiked with acceptable recovery between 80-120%.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size96 well assay
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
03-0125-01 04055977317688