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559400 SB 203580, Iodo- - CAS 189319-35-5 - Calbiochem

A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, p38 MAP Kinase Inhibitor XIII

Primary Target: p38 MAP kinase
559400
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
189319-35-5C₂₁H₁₆IN₃OS
Description
Overview

This product has been discontinued.



A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase. Exhibits similar inhibitory potency as its parent compound SB 203580 (Cat. No. 559389). Useful for the identification of inhibitor binding sites in p38 MAP kinase.
Catalogue Number559400
Brand Family Calbiochem®
Synonyms4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, p38 MAP Kinase Inhibitor XIII
References
ReferencesTong, L., et al. 1997. Nat. Struct. Biol. 4, 311.
Product Information
CAS number189319-35-5
ATP CompetitiveY
FormOff-white solid
Hill FormulaC₂₁H₁₆IN₃OS
Chemical formulaC₂₁H₁₆IN₃OS
ReversibleY
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary Targetp38 MAP kinase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
559400 0

Documentation

SB 203580, Iodo- - CAS 189319-35-5 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

SB 203580, Iodo- - CAS 189319-35-5 - Calbiochem Certificates of Analysis

TitleLot Number
559400

References

Reference overview
Tong, L., et al. 1997. Nat. Struct. Biol. 4, 311.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-April-2011 RFH
Synonyms4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, p38 MAP Kinase Inhibitor XIII
DescriptionA highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase, similar to SB 203580 (Cat. No. 559389). Useful for the identification of inhibitor binding sites of the p38 MAP kinase enzyme.
FormOff-white solid
CAS number189319-35-5
Chemical formulaC₂₁H₁₆IN₃OS
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesTong, L., et al. 1997. Nat. Struct. Biol. 4, 311.