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475818 Microcystin-LW, Microcystis aeruginosa - Calbiochem

Analog of Microcystin-LR with Trp substituted in place of Arg. Believed to be more cell-permeable than other microcystins making it useful for biochemical studies in intact cells.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: MCYST-LW

Primary Target: Protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A)
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₅₄H₇₂N₈O₁₂

Products

Catalogue NumberPackaging Qty/Pack
475818-25UG Alu drum 25 μg
Description
OverviewAnalog of Microcystin-LR (Cat. No. 475815) with Trp substituted in place of Arg. Believed to be more cell-permeable than other microcystins making it useful for biochemical studies in intact cells.
Catalogue Number475818
Brand Family Calbiochem®
SynonymsMCYST-LW
References
ReferencesLawton, L.A., et al. 1995. Nat. Toxins 3, 50.
Lawton, L.A., et al. 1994. Analyst. 119, 1525.
Product Information
ATP CompetitiveN
DeclarationNot available for sale outside of the United States.
FormColorless film
Hill FormulaC₅₄H₇₂N₈O₁₂
Chemical formulaC₅₄H₇₂N₈O₁₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetProtein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A)
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 26/27/28-36/37/38-43

Very toxic by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
May cause sensitization by skin contact.
S PhraseS: 26-36/37/39-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Highly Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
End use certificateY
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
475818-25UG 04055977185614

Documentation

Microcystin-LW, Microcystis aeruginosa - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Microcystin-LW, Microcystis aeruginosa - Calbiochem Certificates of Analysis

TitleLot Number
475818

References

Reference overview
Lawton, L.A., et al. 1995. Nat. Toxins 3, 50.
Lawton, L.A., et al. 1994. Analyst. 119, 1525.

Brochure

Title
Protein Phosphatases Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-August-2008 RFH
SynonymsMCYST-LW
DescriptionAnalog of Microcystin-LR (Cat. No 475815) with Trp group substituted in place of Arg. Believed to be more cell-permeable than other microcystins, making it useful for biochemical studies in intact cells.
FormColorless film
Chemical formulaC₅₄H₇₂N₈O₁₂
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (2.5 mg/ml) or Methanol (2 mg/ml).
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Highly Toxic
ReferencesLawton, L.A., et al. 1995. Nat. Toxins 3, 50.
Lawton, L.A., et al. 1994. Analyst. 119, 1525.